Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Movement Generation with Circuits of Spiking Neurons [PDF]
How can complex movements that take hundreds of milliseconds be generated by stereotypical neural microcircuits consisting of spiking neurons with a much faster dynamics? We show that linear readouts from generic neural microcircuit models can be trained to generate basic arm movements. Such movement generation is independent of the arm model used and
Joshi, Prashant, Maass, Wwolfgang
openaire +4 more sources
Brain-inspired nanophotonic spike computing: challenges and prospects
Nanophotonic spiking neural networks (SNNs) based on neuron-like excitable subwavelength (submicrometre) devices are of key importance for realizing brain-inspired, power-efficient artificial intelligence (AI) systems with high degree of parallelism and ...
Bruno Romeira +19 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Prospective Coding by Spiking Neurons
Animals learn to make predictions, such as associating the sound of a bell with upcoming feeding or predicting a movement that a motor command is eliciting. How predictions are realized on the neuronal level and what plasticity rule underlies their learning is not well understood.
Johanni Brea +3 more
openaire +5 more sources
A VLSI neuromorphic device for implementing spike-based neural networks [PDF]
Indiveri G, Chicca E. A VLSI neuromorphic device for implementing spike-based neural networks. Presented at the Proceedings of the 21st Italian Workshop on Neural Nets (WIRN).We present a neuromorphic VLSI device which comprises hybrid analog/digital ...
Morabito, C. F. +5 more
core +1 more source
Performing Arithmetic Operations with Locally Homogeneous Spiking Neural P Systems
The parallelism of rule execution in membrane computing provides support for improving computational efficiency. Membrane computing models have been applied in many fields.
Xu Zhang +3 more
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Function approximation with uncertainty propagation in a VLSI spiking neural network [PDF]
The brain combines and integrates multiple cues to take coherent, context-dependent action using distributed, event-based computational primitives. Computational models that use these principles in software simulations of recurrently coupled spiking ...
Sonnleithner, D. +20 more
core +1 more source
In Materia Neuron Spiking Plasticity for Sequential Event Processing Based on Dual‐Mode Memristor
Artificial neurons are the fundamental elements in neuromorphic computing systems. Studies have revealed neuronal spike‐rate adaptation owing to intrinsic plasticity that neurons will adapt to the spiking patterns and store the events in the background ...
Linbo Shan +9 more
doaj +1 more source

