Results 91 to 100 of about 2,427,104 (377)

Interaction of Catechins with Human Erythrocytes

open access: yesMolecules, 2020
The aim of this study was to characterize the interaction of chosen catechins ((+)-catechin, (−)-epigallocatechin (EGC), and (−)-epigallocatechin gallate (EGCG)) with human erythrocytes and their protective effects against oxidative damage of
Katarzyna Naparlo   +5 more
doaj   +1 more source

From Fractional Chern Insulators to a Fractional Quantum Spin Hall Effect

open access: yes, 2012
We investigate the algebraic structure of flat energy bands a partial filling of which may give rise to a fractional quantum anomalous Hall effect (or a fractional Chern insulator) and a fractional quantum spin Hall effect. Both effects arise in the case
A.L. Efros   +26 more
core   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Conformation and Membrane Topology of the N-Terminal Ectodomain of Influenza A M2 Protein

open access: yesMembranes
The N-terminal ectodomain of the influenza A M2 protein is a target for universal influenza vaccine development and novel antiviral strategies. Despite the significance of this domain, it is poorly understood and most structural studies of the M2 protein
Kyra C. Roepke, Kathleen P. Howard
doaj   +1 more source

Line operators of gauge theories on non-spin manifolds

open access: yesJournal of High Energy Physics, 2020
We study four-dimensional gauge theories on oriented and non-spin spacetime manifolds. On such manifolds, each line operator arises only either as a boson or a fermion. Based on physical arguments, a method of systematically assigning spin labels to line
J.P. Ang   +2 more
doaj   +1 more source

Simulation vs. reality: a comparison of in silico distance predictions with DEER and FRET measurements. [PDF]

open access: yesPLoS ONE, 2012
Site specific incorporation of molecular probes such as fluorescent- and nitroxide spin-labels into biomolecules, and subsequent analysis by Förster resonance energy transfer (FRET) and double electron-electron resonance (DEER) can elucidate the distance
Daniel Klose   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

The Morphology of N=6 Chern-Simons Theory

open access: yes, 2009
We tabulate various properties of the language of N=6 Chern-Simons Theory, in the sense of Polyakov. Specifically we enumerate and compute character formulas for all syllables of up to four letters, i.e.
A. Hanany   +38 more
core   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

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