Results 61 to 70 of about 37,070 (307)

Interaction of Catechins with Human Erythrocytes

Molecules, 2020
The aim of this study was to characterize the interaction of chosen catechins ((+)-catechin, (−)-epigallocatechin (EGC), and (−)-epigallocatechin gallate (EGCG)) with human erythrocytes and their protective effects against oxidative damage of
Katarzyna Naparlo, Grzegorz Bartosz, Ireneusz Stefaniuk, Bogumil Cieniek, Miroslaw Soszynski, Izabela Sadowska-Bartosz   +5 more
doaj   +1 more source

Amide Proton Transfer Imaging- Arterial Spin Labeling Mismatch - a New Imaging Biomarker for Pilocytic Astrocytoma [PDF]

, 2023
Adhithyan Rajendran, Natesan Chidambaranathan, Prashant Jawahar, Sushama Patil, Srinivas Chilukuri, Siddhartha Ghosh, Roopesh Kumar, Rakesh Jalali   +7 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Line operators of gauge theories on non-spin manifolds

Journal of High Energy Physics, 2020
We study four-dimensional gauge theories on oriented and non-spin spacetime manifolds. On such manifolds, each line operator arises only either as a boson or a fermion. Based on physical arguments, a method of systematically assigning spin labels to line
J.P. Ang, Konstantinos Roumpedakis, Sahand Seifnashri   +2 more
doaj   +1 more source

Simulation vs. reality: a comparison of in silico distance predictions with DEER and FRET measurements. [PDF]

PLoS ONE, 2012
Site specific incorporation of molecular probes such as fluorescent- and nitroxide spin-labels into biomolecules, and subsequent analysis by Förster resonance energy transfer (FRET) and double electron-electron resonance (DEER) can elucidate the distance
Daniel Klose, Johann P Klare, Dina Grohmann, Christopher W M Kay, Finn Werner, Heinz-Jürgen Steinhoff   +5 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

The Influence of Blood and Serum Microenvironment on Spin-Labeled Magnetic Nanoparticles

Magnetism
The investigation and clarification of the properties of surface-functionalized superparamagnetic nanoparticles in a biological environment are key challenges prior to their medical applications.
Tomasz Kubiak
doaj   +1 more source

A novel strategy for site selective spin-labeling to investigate bioactive entities by DNP and EPR spectroscopy

Scientific Reports, 2021
A novel specific spin-labeling strategy for bioactive molecules is presented for eptifibatide (integrilin) an antiplatelet aggregation inhibitor, which derives from the venom of certain rattlesnakes.
Kevin Herr, Max Fleckenstein, Martin Brodrecht, Mark V. Höfler, Henrike Heise, Fabien Aussenac, Torsten Gutmann, Michael Reggelin, Gerd Buntkowsky   +8 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Conformation and Membrane Topology of the N-Terminal Ectodomain of Influenza A M2 Protein

Membranes
The N-terminal ectodomain of the influenza A M2 protein is a target for universal influenza vaccine development and novel antiviral strategies. Despite the significance of this domain, it is poorly understood and most structural studies of the M2 protein
Kyra C. Roepke, Kathleen P. Howard
doaj   +1 more source