Results 51 to 60 of about 1,355,397 (313)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

An unusual presentation of spontaneous spinal epidural hematoma

Journal of the American College of Emergency Physicians Open, 2023
We report a rare case of spontaneous spinal epidural hematoma. Various presentations may occur, most commonly including neck pain, interscapular pain, radicular pain, and paralysis.
Brian L. Risavi, Erin M. Reese, Mary Knott   +2 more
doaj   +1 more source

Trajectory and Determinant of Functional Independence Among Patient with Traumatic and Non-Traumatic Spinal Cord Injury [PDF]

, 2018
The level of functional independence was directly proportional to life satisfaction and quality of life in patients with spinal cord injury. By knowing the determinants that predict changes in functional independence, medical treatment and rehabilitation
Ferdiana, A. (Astri), Lanodiyu, Z. A. (Zikrina), Magetsari, R. (Rahadyan), Putramega, D. (Dananjaya), Sakadewa, G. P. (Galih), Sakti, Y. M. (Yudha)   +5 more
core  

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico, Becker, Wiebke, Brenneis, Christian, Coste, Ovidiu, Geisslinger, Gerd, Nusing, Rolf M., Popp, Laura, Schmidt, Ronald, Scholich, Klaus   +8 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Patterns of lipofuscin accumulation in ganglionic nerve cells of superior cervical ganglion in humans [PDF]

Vojnosanitetski Pregled, 2008
Background/Aim. Considering available literature lipofuscin is a classical age pigment of postmitotic cells, and a consistently recognized phenomenon in humans and animals.
Živković Vladimir, Stefanović Natalija, Đurović-Filipović Tatjana, Pavlović Snežana, Stojanović Vesna, Bakić Mirjana, Kundalić Braca, Pavlović Miljana   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Norepinephrine Versus Phenylephrine for the Prevention of Post Spinal Hypotension in Caesarean Section.

Journal of Karnali Academy of Health Sciences, 2022
Background: Hypotension following spinal anesthesia in the cesarean section is common despite adequate fluid loading. The recommended medication to treat spinal hypotension during cesarean section is phenylephrine. Norepinephrine bolus has recently been
Nabin Thapa, Pradip Raj Vaidya, Sangeeta Shrestha, Sabina Thapa   +3 more
doaj  

Extradural spinal meningioma: Revisiting a rare entity

Journal of Craniovertebral Junction and Spine, 2016
Spinal meningiomas are mostly intradural in location although at times these are associated with some extradural extensions. Purely extradural spinal meningiomas (EDSMs) are however, extremely rare and when present, may cause diagnostic dilemma ...
Guruprasad Bettaswamy, Paurush Ambesh, Kuntal Kanti Das, Rabi Sahu, Arun Srivastava, Anant Mehrotra, Awadhesh Jaiswal, Sushila Jaiswal, Sanjay Behari   +8 more
doaj   +1 more source

Clinical Characteristics and Outcomes Among Individuals With Spinal Implant Infections: A Descriptive Study. [PDF]

, 2016
Little is known about the clinical presentation and outcomes associated with spinal implant infections. Here, we describe a single center's experience in a retrospective cohort of 109 individuals with spinal implant infections, including clinical ...
Baxi, Sanjiv M, Doernberg, Sarah B, Grill, Marie F, Liu, Catherine, Robinson, Makeda L, Schwartz, Brian S   +5 more
core   +1 more source