Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Role of mTOR and VEGFR Inhibition in Prevention of Metastatic Tumor Growth in the Spine [PDF]
Objective: Spinal metastatic disease remains a major problem of oncological diseases. Patients affectedmay suffer pain, spinal instability, and severe neurological deficits. Today, palliative surgery and radiotherapy are the mainstays of therapy.
Broggini, Thomas+4 more
core +1 more source
Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]
Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
core +1 more source
Objective: To determine the efficacy of intramuscular phenylephrine for maintenance of maternal hemodynamics in caesarean section under spinal anesthesia. Study Design: Case series.
Muhammad Saeed+5 more
doaj
SPIRAP Wireless Uplink Random Access Protocol Using Spinal Code [PDF]
In this paper we present SPIRAP, SPinal Random Access Protocol, a new method for multiuser detection over wireless fading channel. SPIRAP combines sequential decoding with rateless Spinal code. SPIRAP appears to be an efficient protocol for transmitting small packets in a minimally controlled network and can be attractive for the Internet of Things ...
arxiv
Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord [PDF]
To restore function after injury to the CNS, axons must be stimulated to extend into denervated territory and, critically, must form functional synapses with appropriate targets. We showed previously that forced overexpression of the transcription factor
Balle, Eric+8 more
core +2 more sources
Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury [PDF]
Many studies highlight the remarkable plasticity demonstrated by spinal circuits following an incomplete spinal cord injury (SCI). Such plasticity can contribute to improvements in volitional motor recovery, such as walking function, although similar ...
Hornby, T. George+2 more
core +1 more source
Spinal column shortening versus revision detethering for recurrent adult tethered cord syndrome: a preliminary comparison of perioperative and clinical outcomes. [PDF]
OBJECTIVE:Recurrent tethered cord syndrome (TCS), believed to result from tension on the distal portion of the spinal cord, causes a constellation of neurological symptoms. Detethering surgery has been the traditional treatment for TCS. However, in cases
Chang, Chih-Chang+7 more
core +1 more source