Results 61 to 70 of about 11,861 (217)

Bioimaging of sense organs and the central nervous system in extant fishes and reptiles in situ: A review

The Anatomical Record, EarlyView.
Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin, Kara E. Yopak, Jenna M. Crowe‐Riddell, Victoria Camilieri‐Asch, Caroline C. Kerr, Hope Robins, Myoung Hoon Ha, Annalise Ceddia, Travis L. Dutka, Lucille Chapuis   +9 more
wiley   +1 more source

Disentangling balance impairments in spinal and bulbar muscular atrophy

Neuroscience Letters, 2019
Spinal and bulbar muscular atrophy (Kennedy's disease) has been associated with balance dysfunction and falls. However, postural control has not been studied quantitatively. Here, we quantified upright stance and aimed to disentangle the role of vestibular, proprioceptive and oculomotor deficits.
Anagnostou, E., Zachou, A., Breza, M., Kladi, A., Karadima, G., Koutsis, G.   +5 more
openaire   +3 more sources

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy [PDF]

Neurology, 2017
To determine the prevalence and features of fatty liver disease in spinal and bulbar muscular atrophy (SBMA).Two groups of participants with SBMA were evaluated. In the first group, 22 participants with SBMA underwent laboratory analysis and liver imaging.
Guber, Robert D., Takyar, Varun, Kokkinis, Angela, Fox, Derrick A., Alao, Hawwa, Kats, Ilona, Bakar, Dara, Remaley, Alan T., Hewitt, Stephen M., Kleiner, David E., Liu, Chia-Ying, Hadigan, Colleen, Fischbeck, Kenneth H., Rotman, Yaron, Grunseich, Christopher   +14 more
openaire   +2 more sources

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Differential diagnosis in spinal and bulbar muscular atrophy clinical and molecular aspects [PDF]

, 1995
Kennedy disease is caused by an enlarged trinucleotide repeat sequence within the androgen receptor gene. We report here seven male patients with a benign motor neuron syndrome highly analogous to Kennedy disease but with a normal trinucleotide ...
Baas, F. (Frank), Bolhuis, P.A. (P.), Brüggenwirth, H.T. (Hennie), Busch, H.F.M. (Herman), Jong, J.M.B.V. (Vianney) de, Jöbsis, G.J. (G.), Koelman, J.H.T.M. (Johannes ), Louwerse, I. (Ilse), Visser, M. (Marianne) de, Wiersinga, W.M. (Wilmar), Wolterman, R.A. (Ruud)   +10 more
core   +1 more source

Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review

Movement Disorders, EarlyView.
Abstract Background Most individuals with Parkinson's disease (PD) develop dysphagia during the course of their disease. It is crucial to comprehensively understand swallowing characteristics specific to PD for effective treatment. Objectives To systematically analyze and synthesize swallowing characteristics in people with PD compared with healthy ...
Kerstin Erfmann, Julia Hirschwald, Jule Hofacker, Katharina Winiker, Juliane Klann, Rainer Dziewas, Tobias Warnecke   +6 more
wiley   +1 more source

CHCHD10 mutations and motor neuron disease: the distribution in Finnish patients. [PDF]

, 2016
Peer ...
Auranen, Mari, Jokela, Manu, Lähdesmäki, Janne, Palmio, Johanna, Penttilä, Sini, Sandell, Satu, Saukkonen, Anna Maija, Shcherbii, Mariia, Toivanen, Jari, Tyynismaa, Henna, Udd, Bjarne, Ylikallio, Emil   +11 more
core   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Differentiating lower motor neuron syndromes [PDF]

, 2017
Lower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and may arise from pathology affecting the distal motor nerve up to the level of the anterior horn cell. A variety of hereditary causes are recognised, including spinal
Cornblath, DR, Garg, N, Howells, J, Huynh, W, Kiernan, MC, Krishnan, AV, Matamala, JM, Park, SB, Pollard, JD, Reilly, MM, Spies, J, Vucic, S, Yiannikas, C   +12 more
core