Results 131 to 140 of about 186,334 (351)

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

EFFICACY OF INTRAMUSCULAR PHENYLEPHRINE FOR MAINTENANCE OF MATERNAL HEMODYNAMICS IN CAESAREAN SECTION UNDER SPINAL ANAESTHESIA

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To determine the efficacy of intramuscular phenylephrine for maintenance of maternal hemodynamics in caesarean section under spinal anesthesia. Study Design: Case series.
Muhammad Saeed   +5 more
doaj  

Relation between fentanyl dose and patient state index during spinal anesthesia for elective cesarean section [PDF]

open access: gold, 2016
Hiroki Iwata   +6 more
openalex   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu   +10 more
wiley   +1 more source

Spinal anesthesia: should everyone receive a urinary catheter?: a randomized, prospective study of patients undergoing total hip arthroplasty. [PDF]

open access: yes, 2013
BACKGROUND: The objective of this randomized prospective study was to determine whether a urinary catheter is necessary for all patients undergoing total hip arthroplasty under spinal anesthesia.
Gandhi, MD, Kishor   +6 more
core   +2 more sources

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

open access: yesAdvanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi   +11 more
wiley   +1 more source

Ultrasonographic Carotid Artery Flow Measurements as Predictors of Spinal Anesthesia-Induced Hypotension in Elderly Patients: A Prospective Observational Study

open access: green, 2022
Hyae Jin Kim   +8 more
openalex   +2 more sources

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