Results 131 to 140 of about 1,038,908 (406)

The free energy of biomembrane and nerve excitation and the role of anesthetics

open access: yes, 2018
In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference ...
Heimburg, Thomas   +3 more
core   +1 more source

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

open access: yesAdvanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu   +8 more
wiley   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

open access: yesAdvanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch   +13 more
wiley   +1 more source

Shivering Management in Spinal Anesthesia: Evaluating the Role of Ketamine: A Narrative Review

open access: yesArchives of Anesthesia and Critical Care
Background: Shivering is one of the most prevalent known complications due to dysregulation in the thermoregulatory system following regional anesthesia, with an incidence of 65%, leading to unpleasant outcomes and decreased patient satisfaction ...
Siavash Sangi   +5 more
doaj   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

open access: yesAdvanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang   +13 more
wiley   +1 more source

Paresthesia in Spinal Anesthesia [PDF]

open access: yes, 2012
Spinal anesthesia is induced by injecting small amounts of local anesthetic into the cerebrospinal fluid (CSF), which solution must be capable of blocking nerve paths, and non-toxic, that is, it should not hinder the proper functioning of the bulbar centers, or interfere with the metabolic processes of the more important organs.
Luiz Eduardo Imbelloni   +1 more
openaire   +3 more sources

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

open access: yesAdvanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu   +13 more
wiley   +1 more source

The effect of teaching on the completeness of the anesthesia record charts for obstetric subarachnoid blocks in a low resource area hospital

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2015
Background: Spinal anesthesia is a widely practiced anesthetic technique for cesarean delivery. Record charting and keeping during obstetric spinal anesthesia demand accuracy and completeness for patient′s safety, medico-legal and research purposes. This
Simeon Olugbade Olateju   +2 more
doaj   +1 more source

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