Results 41 to 50 of about 125,751 (335)
Advanced Healthcare Materials, EarlyView.This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer +10 more
wiley +1 more source
Information and Communication Theoretical Understanding and Treatment of Spinal Cord Injuries: State-of-the-art and Research Challenges [PDF]
, 2020 Among the various key networks in the human body, the nervous system occupies central importance. The debilitating effects of spinal cord injuries (SCI) impact a significant number of people throughout the world, and to date, there is no satisfactory method to treat them.
arxiv +1 more source
Biomarkers in spinal cord injury [PDF]
Spinal Cord, 2009 Literature review.In traumatic spinal cord injury (SCI), much effort has been put into the evaluation of SCI severity and the prediction of recovery potential. An accurate prediction of the initial damage of the spinal cord that differentiates between the severities of SCI however, may help physicians in choosing a particular neuroprotective treatment ...
Pouw, Martin +5 more
openaire +5 more sources
Advanced Healthcare Materials, EarlyView.Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor +10 more
wiley +1 more source
Mechanisms of isolated spinal cord injury in children
Хирургия позвоночника, 2016 Objective. To study the mechanisms of spinal cord injury in children of different age groups. Material and Methods. А retrospective analysis of the results of treatment of 217 children aged 1 to 15 years with trau- matic injuries of the spine and ...
Igor I. Larkin +5 more
doaj +1 more source
Predictors of complications and mortality in traumatic spinal cord injuries
Кубанский научный медицинский вестник, 2020 Background. One of the most common causes of death is trauma. The World Health Organization predicts a 40 % increase in injuries and injury-related deaths over the next 10 years.
Lyudmila M. Mirzaeva +4 more
doaj +1 more source
A Generalized Correlation Index for Quantifying Signal Morphological Similarity [PDF]
, 2016 In biomedical applications, the similarity between a signal measured from an injured subject and a reference signal measured from a normal subject can be used to quantify the injury severity. This paper proposes a generalization of the adaptive signed correlation index (ASCI) to account for specific signal features of interest and extend the ...
arxiv +1 more source
High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks
Advanced Materials, EarlyView.3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger +7 more
wiley +1 more source
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Advanced Materials, EarlyView.This review explores the integration of responsive materials and soft robotic actuators with implantable electronics to address key challenges in bioelectronic medicine. By enabling shape actuation, these technologies improve deployment, adaptability, and accuracy in minimally invasive procedures.
Chaoqun Dong, George G. Malliaras
wiley +1 more source