Results 41 to 50 of about 90,414 (311)

Community-based activity-based therapy for spinal cord injuries rehabilitation

, 2023
This chapter addresses theoretical and practical aspects of the application of activity-based therapies in community settings for people with spinal cord injuries.
de Oliveira, CQ, Padula, N
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Baseline predictors of in-hospital mortality after acute traumatic spinal cord injury: data from a level I trauma center

Scientific Reports, 2022
Comorbidity scores are important predictors of in-hospital mortality after traumatic spinal cord injury (tSCI), but the impact of specific pre-existing diseases is unknown.
Christian Blex, Martin Kreutzträger, Johanna Ludwig, Claus Peter Nowak, Jan M. Schwab, Tom Lübstorf, Axel Ekkernkamp, Marcel A. Kopp, Thomas Liebscher   +8 more
doaj   +1 more source

Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons

, 2008
Although most spinal cord injuries are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions.
Hunanyan, Arsen, John K. Robinson, Schnell, Lisa, Golshani, Roobeh, Li Lou, Roobeh Golshani, Lou, Li, Robinson, John, Lisa Schnell, Ghosh, Arko, Victor L. Arvanian, Schwab, Martin, Damien D. Pearse, Arvanian, Victor, Arsen Hunanyan, Martin E. Schwab, Arko Ghosh, Mendell, Lorne, James W. Fawcett, Lorne M. Mendell, Pearse, Damien, Fawcett, James   +21 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Mine blast injury of the spine and spinal cord: a case report

Ukrainian Neurosurgical Journal, 2022
Many soldiers who were wounded during the war in Ukraine with Russia increased the number of cases of spinal injury. As a result of the Russia-Ukraine war, the number of patients with spine and spinal cord injuries increased significantly ...
Ievgenii I. Slynko, Yurii V. Derkach, Arthur I. Ermolev, Oleksii S. Nekhlopochyn, David A. Tavzadze   +4 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Epidemiology of spinal cord injuries and risk factors for complete injuries in Guangdong, China: a retrospective study. [PDF]

PLoS ONE, 2014
BACKGROUND: Spinal cord injuries are highly disabling and deadly injuries. Currently, few studies focus on non-traumatic spinal cord injuries, and there is little information regarding the risk factors for complete injuries.
Rui Yang, Lan Guo, Peng Wang, Lin Huang, Yong Tang, Wenhao Wang, Keng Chen, Jichao Ye, Ciyong Lu, Yanfeng Wu, Huiyong Shen   +10 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source