Results 71 to 80 of about 193,351 (379)
Novel Advancements in Three-Dimensional Neural Tissue Engineering and Regenerative Medicine [PDF]
Neural Regen. Res. 2015;10(3):352-4, 2015 Neurological diseases and injuries present some of the greatest challenges in modern medicine, often causing irreversible and lifelong burdens in the people whom they afflict. These diagnoses have devastating consequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural ...
arxiv +1 more source
A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]
, 2018 Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A. +7 more
core +1 more source
A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides
Advanced Healthcare Materials, EarlyView.Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley +2 more
wiley +1 more source
A Generalized Correlation Index for Quantifying Signal Morphological Similarity [PDF]
, 2016 In biomedical applications, the similarity between a signal measured from an injured subject and a reference signal measured from a normal subject can be used to quantify the injury severity. This paper proposes a generalization of the adaptive signed correlation index (ASCI) to account for specific signal features of interest and extend the ...
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia +7 more
wiley +1 more source
Archives of Rehabilitation Research and Clinical Translation, 2022 Since the 1990s, Veterans Health Administration (VHA) has maintained a registry of Veterans with Spinal Cord Injuries and Disorders (SCI/Ds) to guide clinical care, policy, and research. Historically, methods for collecting and recording data for the VHA
Jennifer L. Sippel, PhD +11 more
doaj
Advanced Healthcare Materials, EarlyView.Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang +6 more
wiley +1 more source
Development And Validation Of A Medical Home Model For Persons With Spinal Cord Injuries In An Acute Rehabilitation Outpatient Specialty Center [PDF]
, 2018 Background: Primary care is difficult for patients with spinal cord injuries to find. As such, these patients typically turn to rehabilitation centers and clinics that do not provide primary care services.
Limbaga, Aries
core +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source