Results 71 to 80 of about 84,237 (265)

T-cell biomarkers improve urinary tract infection risk stratification beyond clinical characteristics after acute traumatic spinal cord injury

Scientific Reports
Patients with traumatic spinal cord injury (SCI) frequently develop urinary tract infections (UTI) which may compromise neurological rehabilitation. We explored risk factors for UTI, including immunological biomarkers, in patients with acute traumatic ...
Oliver Schweizerhof, Christian Meisel, Christian Blex, Paolo Cinelli, Ralf Watzlawick, Tom Lübstorf, Laura-Christin Geurtz, Martin Kreutzträger, Elias Baumgartner, Julian Hirt, Magdalena Hoppe, Nadine Unterwalder, Uwe Kölsch, Ralf Böthig, Burkhard Domurath, Claudia Druschel, Klaus-Dieter Schaser, Andreas Niedeggen, Armin Curt, Michael G. Fehlings, Peter Vajkoczy, Axel Ekkernkamp, Thomas Liebscher, Jan M. Schwab, Marcel A. Kopp, Ulrike Grittner   +25 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Predictors of complications and mortality in traumatic spinal cord injuries

Кубанский научный медицинский вестник, 2020
Background. One of the most common causes of death is trauma. The World Health Organization predicts a 40 % increase in injuries and injury-related deaths over the next 10 years.
Lyudmila M. Mirzaeva, Sergei V. Lobzin, Inga V. Chistova, Olga A. Rizahanova, Alexander A. Dulaev   +4 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

Advanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko, Chiamaka Akah, Ravinder Dahiya   +2 more
wiley   +1 more source

Linking neurological status to functional outcomes in spinal cord injury: a multi-class, task-specific approach

BMC Biomedical Engineering
Background Spinal cord injury (SCI) causes long-term neurological deficits resulting in functional disabilities. While longitudinal recovery patterns of sensorimotor outcomes after SCI have been studied, few analyses have applied machine learning to ...
Miklovana Tuci, Lena Steck, Louis P. Lukas, Olga Taran, Ruediger Rupp, Norbert Weidner, Martin Schubert, Frank Röhrich, Josina Waldmann, Yorck B. Kalke, Rainer Abel, Doris Maier, Thomas Liebscher, Björn Zörner, Armin Curt, Marc Bolliger, Sarah C. Brüningk, Catherine R. Jutzeler   +17 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Spinal Cord Injured Patients: Bait for Research in the Current Millennium

Acta Medica Iranica, 2015
No ...
Mehdi Zeinalizadeh, Zahid Hussain Khan
doaj  

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source