Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord [PDF]
, 2016 To restore function after injury to the CNS, axons must be stimulated to extend into denervated territory and, critically, must form functional synapses with appropriate targets. We showed previously that forced overexpression of the transcription factor
Balle, Eric +8 more
core +2 more sources
Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications
Advanced Healthcare Materials, EarlyView.The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho +4 more
wiley +1 more source
Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction [PDF]
, 2018 The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands.
Blackmore, Murray G. +4 more
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Scientific ReportsIntra-epidermal electrically evoked potentials (IEEPs) might represent a promising method for an improved characterization of certain spinal pathologies. Before successful clinical implementation, investigating IEEPs reliability is a prerequisite.
Sara U. Júlio +5 more
doaj +1 more source
Smart Catheters for Diagnosis, Monitoring, and Therapy
Advanced Healthcare Materials, EarlyView.This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury. [PDF]
, 2015 Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms ...
Beattie, Michael S +7 more
core +1 more source
Microenvironment Imbalance of Spinal Cord Injury
Cell Transplantation, 2018 Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient physiology and psychology. The microenvironment of the injured spinal cord is complicated.
Baoyou Fan +9 more
semanticscholar +1 more source
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Design, control and evaluation of a low-cost active orthosis for the gait of spinal cord injured subjects [PDF]
, 2016 Robotic gait training after spinal cord injury is of high priority to maximize independence and improve the living conditions of the patients. Current rehabilitation robots are expensive and heavy, and are generally found only in the clinical environment.
Alonso Sánchez, Francisco Javier +6 more
core
The relationship between perfectionistic self-presentation and reactions to impairment and disability following spinal cord injury [PDF]
, 2016 Univariate and multivariate relationships between perfectionistic self-presentation and reactions to impairment and disability following spinal cord injury were examined. One hundred and forty-four adults with spinal cord injury (M = 48.18 years, SD = 15.
Astill, SL +3 more
core +1 more source