Results 91 to 100 of about 670,877 (408)

Direct Ink Writing of Conductive Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho   +6 more
wiley   +1 more source

Novel Advancements in Three-Dimensional Neural Tissue Engineering and Regenerative Medicine [PDF]

open access: yesNeural Regen. Res. 2015;10(3):352-4, 2015
Neurological diseases and injuries present some of the greatest challenges in modern medicine, often causing irreversible and lifelong burdens in the people whom they afflict. These diagnoses have devastating consequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural ...
arxiv   +1 more source

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley   +2 more
wiley   +1 more source

A Generalized Correlation Index for Quantifying Signal Morphological Similarity [PDF]

open access: yes, 2016
In biomedical applications, the similarity between a signal measured from an injured subject and a reference signal measured from a normal subject can be used to quantify the injury severity. This paper proposes a generalization of the adaptive signed correlation index (ASCI) to account for specific signal features of interest and extend the ...
arxiv   +1 more source

Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis

open access: yesNeural Regeneration Research, 2019
Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair.
Xue Yao   +14 more
semanticscholar   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Supramolecular Additive Screening to Engineer Microfibrous Rafts for Expansion of Pluripotent Stem Cells in Dynamic Suspension

open access: yesAdvanced Healthcare Materials, EarlyView.
Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang   +6 more
wiley   +1 more source

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury. [PDF]

open access: yes, 2010
Although axonal regeneration after CNS injury is limited, partial injury is frequently accompanied by extensive functional recovery. To investigate mechanisms underlying spontaneous recovery after incomplete spinal cord injury, we administered C7 spinal ...
Beattie, Michael S   +13 more
core  

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

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