Results 11 to 20 of about 222,712 (316)

Rare case of real-time observation of paralytic deterioration after cervical dislocation in the hyperacute phase

BMC Musculoskeletal Disorders, 2022
Background There have been no prior reports of real-time detailed records leading to complete quadriplegia immediately after fracture dislocation in high-energy trauma. Here, we report a case of cervical dislocation in which the deterioration to complete
Tsutomu Endo, Kota Suda, Takafumi Fukui, Satoko Matsumoto, Miki Komatsu, Masahiro Ota, Chikara Ushiku, Junichi Yamane, Akio Minami, Masahiko Takahata, Norimasa Iwasaki   +10 more
doaj   +1 more source

Data-driven characterization of walking after a spinal cord injury using inertial sensors

Journal of NeuroEngineering and Rehabilitation, 2023
Background An incomplete spinal cord injury (SCI) refers to remaining sensorimotor function below the injury with the possibility for the patient to regain walking abilities.
Charlotte Werner, Meltem Gönel, Irina Lerch, Armin Curt, László Demkó   +4 more
doaj   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng   +12 more
doaj   +1 more source

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

BMC Neurology, 2021
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug, Tamara Spingler, Cornelia Hensel, Stefan Fichtner, Tiziana Daniel, Laura Heutehaus, Michel Wensing, Rüdiger Rupp, Norbert Weidner   +8 more
doaj   +1 more source

Delayed lumbar plexus palsy due to giant psoas hematoma associated with vertebral compression fracture and direct oral anticoagulants: a case report

BMC Musculoskeletal Disorders, 2021
Background Osteoporotic vertebral compression fractures (VCFs) are commonly observed in elderly people and can be treated by conservatively with minimal risk of complications in most cases.
Chikako Ishii, Miki Komatsu, Kota Suda, Masahiko Takahata, Satoko Matsumoto Harmon, Masahiro Ota, Takamasa Watanabe, Mitsuru Asukai, Norimasa Iwasaki, Akio Minami   +9 more
doaj   +1 more source

Cold evoked potentials elicited by rapid cooling of the skin in young and elderly healthy individuals

Scientific Reports, 2022
Cold-evoked potentials (CEPs) constitute a novel electrophysiological tool to assess cold-specific alterations in somatosensory function. As an important step towards the clinical implementation of CEPs as a diagnostic tool, we evaluated the feasibility ...
Paulina Simonne Scheuren, Natascha Nauer, Jan Rosner, Armin Curt, Michèle Hubli   +4 more
doaj   +1 more source

Mind your step: Target walking task reveals gait disturbance in individuals with incomplete spinal cord injury

Journal of NeuroEngineering and Rehabilitation, 2022
Background Walking over obstacles requires precise foot placement while maintaining balance control of the center of mass (CoM) and the flexibility to adapt the gait patterns.
Freschta Mohammadzada, Carl Moritz Zipser, Chris A. Easthope, David M. Halliday, Bernard A. Conway, Armin Curt, Martin Schubert   +6 more
doaj   +1 more source

Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3

Scientific Reports, 2023
The integrated stress response (ISR)-activated transcription factors ATF4 and CHOP/DDIT3 may regulate oligodendrocyte (OL) survival, tissue damage and functional impairment/recovery in white matter pathologies, including traumatic spinal cord injury (SCI)
Yonglin Gao, George Z. Wei, Michael D. Forston, Benjamin Rood, Emily R. Hodges, Darlene Burke, Kariena Andres, Johnny Morehouse, Christine Armstrong, Charles Glover, Lukasz P. Slomnicki, Jixiang Ding, Julia H. Chariker, Eric C. Rouchka, Sujata Saraswat Ohri, Scott R. Whittemore, Michal Hetman   +16 more
doaj   +1 more source

Overground walking patterns after chronic incomplete spinal cord injury show distinct response patterns to unloading

Journal of NeuroEngineering and Rehabilitation, 2018
Background Body weight support (BWS) is often provided to incomplete spinal cord injury (iSCI) patients during rehabilitation to enable gait training before full weight-bearing is recovered.
Christopher Schmidt Easthope, Luca Renato Traini, Lea Awai, Martina Franz, Georg Rauter, Armin Curt, Marc Bolliger   +6 more
doaj   +1 more source

Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury

Cell Death and Disease, 2023
Macrophage/microglia polarization acts as an important part in regulating inflammatory responses in spinal cord injury (SCI). However, the regulation of inflammation of Schwann cell-derived exosomes (SCDEs) for SCI repair is still unclear.
Jie Ren, Bin Zhu, Guangjin Gu, Wencan Zhang, Junjin Li, Hongda Wang, Min Wang, Xiaomeng Song, Zhijian Wei, Shiqing Feng   +9 more
doaj   +1 more source