Results 11 to 20 of about 670,877 (408)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls   +9 more
wiley   +1 more source

Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]

open access: yes, 2020
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core   +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

open access: yesCell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu   +12 more
doaj   +1 more source

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

open access: yesBMC Neurology, 2021
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug   +8 more
doaj   +1 more source

Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms

open access: yesInternational Journal of Molecular Sciences, 2020
Spinal cord injury (SCI) is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and chronic phases and incorporates a cascade of destructive events such as ...
A. Anjum   +8 more
semanticscholar   +1 more source

Delayed lumbar plexus palsy due to giant psoas hematoma associated with vertebral compression fracture and direct oral anticoagulants: a case report

open access: yesBMC Musculoskeletal Disorders, 2021
Background Osteoporotic vertebral compression fractures (VCFs) are commonly observed in elderly people and can be treated by conservatively with minimal risk of complications in most cases.
Chikako Ishii   +9 more
doaj   +1 more source

Spinal Cord Injuries [PDF]

open access: yesMedical Journal Armed Forces India, 2010
Spinal Cord injury (SCI) is one of the most devastating and demoralizing ailment for both the patient and the medical practitioner. However, with the better understanding of the pathophysiology, better imaging modalities and emphasis on immobilization and rehabilitation has provided a ray of hope to such patients.
SM Sudambrekar, M Malhotra, HS Bhatoe
openaire   +3 more sources

Cold evoked potentials elicited by rapid cooling of the skin in young and elderly healthy individuals

open access: yesScientific Reports, 2022
Cold-evoked potentials (CEPs) constitute a novel electrophysiological tool to assess cold-specific alterations in somatosensory function. As an important step towards the clinical implementation of CEPs as a diagnostic tool, we evaluated the feasibility ...
Paulina Simonne Scheuren   +4 more
doaj   +1 more source

Mind your step: Target walking task reveals gait disturbance in individuals with incomplete spinal cord injury

open access: yesJournal of NeuroEngineering and Rehabilitation, 2022
Background Walking over obstacles requires precise foot placement while maintaining balance control of the center of mass (CoM) and the flexibility to adapt the gait patterns.
Freschta Mohammadzada   +6 more
doaj   +1 more source

Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms

open access: yesFrontiers in Neurology, 2019
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial socioeconomic implications for patients and their care-givers. Recent advances in medical management of SCI has significantly improved diagnosis, stabilization,
Arsalan Alizadeh   +2 more
semanticscholar   +1 more source

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