Results 11 to 20 of about 670,877 (408)
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core +1 more source
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu+12 more
doaj +1 more source
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug+8 more
doaj +1 more source
Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms
Spinal cord injury (SCI) is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and chronic phases and incorporates a cascade of destructive events such as ...
A. Anjum+8 more
semanticscholar +1 more source
Background Osteoporotic vertebral compression fractures (VCFs) are commonly observed in elderly people and can be treated by conservatively with minimal risk of complications in most cases.
Chikako Ishii+9 more
doaj +1 more source
Spinal Cord injury (SCI) is one of the most devastating and demoralizing ailment for both the patient and the medical practitioner. However, with the better understanding of the pathophysiology, better imaging modalities and emphasis on immobilization and rehabilitation has provided a ray of hope to such patients.
SM Sudambrekar, M Malhotra, HS Bhatoe
openaire +3 more sources
Cold-evoked potentials (CEPs) constitute a novel electrophysiological tool to assess cold-specific alterations in somatosensory function. As an important step towards the clinical implementation of CEPs as a diagnostic tool, we evaluated the feasibility ...
Paulina Simonne Scheuren+4 more
doaj +1 more source
Background Walking over obstacles requires precise foot placement while maintaining balance control of the center of mass (CoM) and the flexibility to adapt the gait patterns.
Freschta Mohammadzada+6 more
doaj +1 more source
Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial socioeconomic implications for patients and their care-givers. Recent advances in medical management of SCI has significantly improved diagnosis, stabilization,
Arsalan Alizadeh+2 more
semanticscholar +1 more source