Results 41 to 50 of about 723,074 (354)

A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]

, 2018
Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A., Fry, Collin M.E., Qu, Wenrui, Shields, Christopher B., Shields, Lisa B.E., Wu, Xiangbing, Xu, Xiao-Ming, Zhang, Yi Ping   +7 more
core   +1 more source

Ulnar nerve integrity predicts 1-year outcome in cervical spinal cord injury

Neurological Research and Practice, 2019
Background Accurate predictors of neurological recovery after cervical spinal cord injury are needed. Particularly, to tailor adequate rehabilitation plans. However, objective and quantifiable predictors are sparse.
Andreas Hug, Christian Schuld, Bettina Mürle, Markus Böttinger, EMSCI study group, Norbert Weidner, Rüdiger Rupp   +6 more
doaj   +1 more source

The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER

Acta Neuropathologica Communications, 2023
New histological techniques are needed to examine protein distribution in human tissues, which can reveal cell shape and disease pathology connections.
Ryan K. Shahidehpour, Abraham S. Nelson, Lydia G. Sanders, Chloe R. Embry, Peter T. Nelson, Adam D. Bachstetter   +5 more
doaj   +1 more source

Optimizing Filter-Probe Diffusion Weighting in the Rat Spinal Cord for Human Translation [PDF]

, 2017
Diffusion tensor imaging (DTI) is a promising biomarker of spinal cord injury (SCI). In the acute aftermath, DTI in SCI animal models consistently demonstrates high sensitivity and prognostic performance, yet translation of DTI to acute human SCI has ...
Brian D. Schmit, L. Tugan Muftuler, Matthew D. Budde, Nathan P. Skinner, Nathan P. Skinner, Shekar N. Kurpad   +5 more
core   +3 more sources

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury

Nature Communications, 2019
The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI.
V. Bellver-Landete, Floriane Bretheau, Benoit Mailhot, Nicolas Vallières, Martine Lessard, Marie-Ève Janelle, N. Vernoux, M. Tremblay, Tobias Fuehrmann, M. Shoichet, S. Lacroix   +10 more
semanticscholar   +1 more source

Diffusion Imaging in the Rat Cervical Spinal Cord [PDF]

, 2015
Magnetic resonance imaging (MRI) is the state of the art approach for assessing the status of the spinal cord noninvasively, and can be used as a diagnostic and prognostic tool in cases of disease or injury. Diffusion weighted imaging (DWI), is sensitive
Budde, Matthew D., Kurpad, Shekar N., Schmit, Brian D., Zakszewski, Elizabeth   +3 more
core   +2 more sources

Exploring positive adjustment in people with spinal cord injury. [PDF]

, 2013
This study explored adjustment in people with spinal cord injury; data from four focus groups are presented. Thematic analysis revealed four themes, managing goals and expectations, comparison with others, feeling useful and acceptance, showing ...
Burridge, J., Dibb, B., Donovan-Hall, M., Ellis-Hill, Caroline, Rushton, D.   +4 more
core   +1 more source

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

Neurological Research and Practice, 2023
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative ...
Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner   +3 more
doaj   +1 more source

Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
As a commonly used physical intervention, electrical stimulation (ES) has been demonstrated to be effective in the treatment of central nervous system disorders.
Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi   +12 more
doaj   +1 more source

Minimum toe clearance: probing the neural control of locomotion

Scientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen, Christopher S. Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger   +8 more
doaj   +1 more source