Results 51 to 60 of about 1,496,435 (300)

Effect of detraining on bone strength in subjects with chronic spinal cord injury after a period of electrically-stimulated-cycling : a small cohort study [PDF]

, 2009
To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after detraining or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury.
Hunt, Kenneth, Coupaud, Sylvie, Frotzler, Angela, Kakebeeke, Tanja, Perret, Claudio, Eser, Prisca   +5 more
core   +2 more sources

Mediolateral damping of an overhead body weight support system assists stability during treadmill walking

Journal of NeuroEngineering and Rehabilitation, 2020
Background Body weight support systems with three or more degrees of freedom (3-DoF) are permissive and safe environments that provide unloading and allow unrestricted movement in any direction.
M. Bannwart, S. L. Bayer, N. König Ignasiak, M. Bolliger, G. Rauter, C. A. Easthope   +5 more
doaj   +1 more source

The patient-related factors in revision procedures on tibia of patients with osteogenesis imperfecta treated with the Peter-Williams nail

Journal of Orthopaedic Surgery and Research, 2023
Objective To investigate the patient-related factors that affect the revision rate for the tibia in patients with osteogenesis imperfecta treated with the Peter-Williams nail, and to explore the relationship between the risk factors and complications ...
Wenbiao Zhu, Yang Xiong, Bo Li, Hongjiang Yang, Cong Xing, Xiuzhi Ren, Guangzhi Ning   +6 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Targeting bladder function with network-specific epidural stimulation after chronic spinal cord injury

Scientific Reports, 2022
Profound dysfunctional reorganization of spinal networks and extensive loss of functional continuity after spinal cord injury (SCI) has not precluded individuals from achieving coordinated voluntary activity and gaining multi-systemic autonomic control ...
April N. Herrity, Sevda C. Aslan, Samineh Mesbah, Ricardo Siu, Karthik Kalvakuri, Beatrice Ugiliweneza, Ahmad Mohamed, Charles H. Hubscher, Susan J. Harkema   +8 more
doaj   +1 more source

A BSCB-Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2-Targeted Epigenetic Therapy of Spinal Cord Injury. [PDF]

Adv Sci (Weinh)
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Wang Y, Jin B, Li S, Ouyang Q, Xiao Y, Wen J, Lai Y, Wang P, Wang Y, Cui X, Zhang W, Yao M.   +11 more
europepmc   +2 more sources

Prevention of spinal cord injury [PDF]

Injury Prevention, 2014
To coincide with the International Day of Persons with Disabilities, 3 December, WHO has launched the International perspectives on spinal cord injury . This report summarises the best available evidence on the causes, prevention, care and lived experience of people with spinal cord injury (SCI) across the life course and throughout the world.
von Groote PM, Shakespeare T, Officer A
openaire   +3 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Role of chondroitin sulfate proteoglycans (CSPGs) in synaptic plasticity and neurotransmission in mammalian spinal cord. [PDF]

, 2009
Chronic unilateral hemisection (HX) of the adult rat spinal cord diminishes conduction through intact fibers in the ventrolateral funiculus (VLF) contralateral to HX.
Victor L. Arvanian, Guillermo Garcia-Alias, Arsen S. Hunanyan, Joel M. Levine, James W. Fawcett, Lorne M. Mendell   +5 more
core  

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source