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Causes of Spinal Cord Injury [PDF]

Topics in Spinal Cord Injury Rehabilitation, 2013
Knowledge of the causes of spinal cord injury (SCI) and associated factors is critical in the development of successful prevention programs.This study analyzed data from the National SCI Database (NSCID) and National Shriners SCI Database (NSSCID) in the United States to examine specific etiologies of SCI by age, sex, race, ethnicity, day and month of ...
Yuying, Chen, Ying, Tang, Lawrence C, Vogel, Michael J, Devivo   +3 more
openaire   +2 more sources

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

Neurological Research and Practice, 2023
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative ...
Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner   +3 more
doaj   +1 more source

Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
As a commonly used physical intervention, electrical stimulation (ES) has been demonstrated to be effective in the treatment of central nervous system disorders.
Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi   +12 more
doaj   +1 more source

Minimum toe clearance: probing the neural control of locomotion

Scientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen, Christopher S. Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger   +8 more
doaj   +1 more source

Feasibility of visual instrumented movement feedback therapy in individuals with motor incomplete spinal cord injury walking on a treadmill

Frontiers in Human Neuroscience, 2014
Background: Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good motor function an impaired proprioception may result in an insecure gait.
Daniel eSchließmann, Christian eSchuld, Matthias eSchneiders, Steffen eDerlien, Maria eGlöckner, Till eGladow, Norbert eWeidner, Rüdiger eRupp   +7 more
doaj   +1 more source

Neurophysiological markers predicting recovery of standing in humans with chronic motor complete spinal cord injury

Scientific Reports, 2019
The appropriate selection of individual-specific spinal cord epidural stimulation (scES) parameters is crucial to re-enable independent standing with self-assistance for balance in individuals with chronic, motor complete spinal cord injury, which is a ...
Samineh Mesbah, Federica Gonnelli, Claudia A. Angeli, Ayman El-baz, Susan J. Harkema, Enrico Rejc   +5 more
doaj   +1 more source

Trainer in a pocket - proof-of-concept of mobile, real-time, foot kinematics feedback for gait pattern normalization in individuals after stroke, incomplete spinal cord injury and elderly patients

Journal of NeuroEngineering and Rehabilitation, 2018
Background Walking disabilities negatively affect inclusion in society and quality of life and increase the risk for secondary complications. It has been shown that external feedback applied by therapists and/or robotic training devices enables ...
Daniel Schließmann, Maria Nisser, Christian Schuld, Till Gladow, Steffen Derlien, Laura Heutehaus, Norbert Weidner, Ulrich Smolenski, Rüdiger Rupp   +8 more
doaj   +1 more source

Mediolateral damping of an overhead body weight support system assists stability during treadmill walking

Journal of NeuroEngineering and Rehabilitation, 2020
Background Body weight support systems with three or more degrees of freedom (3-DoF) are permissive and safe environments that provide unloading and allow unrestricted movement in any direction.
M. Bannwart, S. L. Bayer, N. König Ignasiak, M. Bolliger, G. Rauter, C. A. Easthope   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reliability of patient-specific gait profiles with inertial measurement units during the 2-min walk test in incomplete spinal cord injury

Scientific Reports
Most established clinical walking tests assess specific aspects of movement function (velocity, endurance, etc.) but are generally unable to determine specific biomechanical or neurological deficits that limit an individual’s ability to walk.
Romina Willi, Charlotte Werner, László Demkó, Rob de Bie, Linard Filli, Björn Zörner, Armin Curt, Marc Bolliger   +7 more
doaj   +1 more source