Spinal cord injury - Open Access .click

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Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]

, 2020
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core +1 more source

Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury

Nature Communications, 2023
The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation.
Ao Fang +21 more
semanticscholar +1 more source

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Cell & Bioscience, 2023
Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of infiltrating
Guangjin Gu +12 more
doaj +1 more source

Spinal Cord Injuries [PDF]

Medical Journal Armed Forces India, 2010
Spinal Cord injury (SCI) is one of the most devastating and demoralizing ailment for both the patient and the medical practitioner. However, with the better understanding of the pathophysiology, better imaging modalities and emphasis on immobilization and rehabilitation has provided a ray of hope to such patients.
M, Malhotra, H S, Bhatoe, S M, Sudambrekar +2 more
openaire +2 more sources

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

BMC Neurology, 2021
Background A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user.
Andreas Hug +8 more
doaj +1 more source

Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms

International Journal of Molecular Sciences, 2020
Spinal cord injury (SCI) is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and chronic phases and incorporates a cascade of destructive events such as ...
A. Anjum +8 more
semanticscholar +1 more source

Delayed lumbar plexus palsy due to giant psoas hematoma associated with vertebral compression fracture and direct oral anticoagulants: a case report

BMC Musculoskeletal Disorders, 2021
Background Osteoporotic vertebral compression fractures (VCFs) are commonly observed in elderly people and can be treated by conservatively with minimal risk of complications in most cases.
Chikako Ishii +9 more
doaj +1 more source

Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway

CNS Neuroscience & Therapeutics, 2021
Spinal cord injury (SCI) involves multiple pathological processes. Ferroptosis has been shown to play a critical role in the injury process. We wanted to explore whether zinc can inhibit ferroptosis, reduce inflammation, and then exert a neuroprotective ...
Ming-hao Ge +8 more
semanticscholar +1 more source

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Lancet Neurology, 2019
Summary Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate.
Spencer L Alice Richard G Marlena S Wcliff Lydia R Nooshin James Theadom Ellenbogen Bannick Montjoy-Venning L +374 more
semanticscholar +1 more source

Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury

Signal Transduction and Targeted Therapy, 2022
Spinal cord injury (SCI) involves diverse injury responses in different cell types in a temporally and spatially specific manner. Here, using single-cell transcriptomic analyses combined with classic anatomical, behavioral, electrophysiological analyses,
Chen Li +19 more
semanticscholar +1 more source

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