Results 41 to 50 of about 710,546 (383)

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury

Nature Communications, 2019
The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI.
V. Bellver-Landete, Floriane Bretheau, Benoit Mailhot, Nicolas Vallières, Martine Lessard, Marie-Ève Janelle, N. Vernoux, M. Tremblay, Tobias Fuehrmann, M. Shoichet, S. Lacroix   +10 more
semanticscholar   +1 more source

Mediolateral damping of an overhead body weight support system assists stability during treadmill walking

Journal of NeuroEngineering and Rehabilitation, 2020
Background Body weight support systems with three or more degrees of freedom (3-DoF) are permissive and safe environments that provide unloading and allow unrestricted movement in any direction.
M. Bannwart, S. L. Bayer, N. König Ignasiak, M. Bolliger, G. Rauter, C. A. Easthope   +5 more
doaj   +1 more source

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

Neurological Research and Practice, 2023
Epidural electrical epinal cord stimulation (ESCS) is an established therapeutic option in various chronic pain conditions. In the last decade, proof-of-concept studies have demonstrated that ESCS in combination with task-oriented rehabilitative ...
Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner   +3 more
doaj   +1 more source

Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury

Brain : a journal of neurology, 2020
In spinal cord injury, the initial mechanical insult may be followed by progressive cord atrophy and neurodegeneration. Zrzavy et al. characterize innate and adaptive inflammatory responses in human spinal cord injury, and show that oxidative injury is a
Tobias Zrzavy, C. Schwaiger, I. Wimmer, T. Berger, J. Bauer, O. Butovsky, J. Schwab, H. Lassmann, R. Höftberger   +8 more
semanticscholar   +1 more source

A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]

, 2018
Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A., Fry, Collin M.E., Qu, Wenrui, Shields, Christopher B., Shields, Lisa B.E., Wu, Xiangbing, Xu, Xiao-Ming, Zhang, Yi Ping   +7 more
core   +1 more source

Feasibility of visual instrumented movement feedback therapy in individuals with motor incomplete spinal cord injury walking on a treadmill

Frontiers in Human Neuroscience, 2014
Background: Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good motor function an impaired proprioception may result in an insecure gait.
Daniel eSchließmann, Christian eSchuld, Matthias eSchneiders, Steffen eDerlien, Maria eGlöckner, Till eGladow, Norbert eWeidner, Rüdiger eRupp   +7 more
doaj   +1 more source

Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
As a commonly used physical intervention, electrical stimulation (ES) has been demonstrated to be effective in the treatment of central nervous system disorders.
Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi   +12 more
doaj   +1 more source

Minimum toe clearance: probing the neural control of locomotion

Scientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen, Christopher S. Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger   +8 more
doaj   +1 more source

The patient-related factors in revision procedures on tibia of patients with osteogenesis imperfecta treated with the Peter-Williams nail

Journal of Orthopaedic Surgery and Research, 2023
Objective To investigate the patient-related factors that affect the revision rate for the tibia in patients with osteogenesis imperfecta treated with the Peter-Williams nail, and to explore the relationship between the risk factors and complications ...
Wenbiao Zhu, Yang Xiong, Bo Li, Hongjiang Yang, Cong Xing, Xiuzhi Ren, Guangzhi Ning   +6 more
doaj   +1 more source

Recovery of Over‐Ground Walking after Chronic Motor Complete Spinal Cord Injury

New England Journal of Medicine, 2018
Persons with motor complete spinal cord injury, signifying no voluntary movement or sphincter function below the level of injury but including retention of some sensation, do not recover independent walking. We tested intense locomotor treadmill training
C. Angeli, M. Boakye, Rebekah A Morton, Justin Vogt, Kristin Benton, Yangsheng Chen, Christie K. Ferreira, S. Harkema   +7 more
semanticscholar   +1 more source