Results 81 to 90 of about 63,554 (339)
Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants. [PDF]
The Genotype-Tissue Expression (GTEx) resource has provided insights into the regulatory impact of genetic variation on gene expression across human tissues; however, thus far has not considered how variation acts at the resolution of the different cell ...
D'Antonio, Matteo +3 more
core
a clinical study protocol [PDF]
Introduction The approved analgesic and anti-inflammatory drugs ibuprofen and indometacin block the small GTPase RhoA, a key enzyme that impedes axonal sprouting after axonal damage.
Blex, Christian +14 more
core +1 more source
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek +18 more
wiley +1 more source
In most series of neoplasms of the spinal canal, spinal cord and its leptomeninges, the incidence of meningioma group comprises approximately 25%. The incidence of multiple meningiomas is small when compared with the frequency of its single occurrence ...
José Alberto Gonçalves da Silva +3 more
doaj +1 more source
Spinal Cord Malformation Containing a Papillary Neoplasm
A 36‐year‐old man had lower back pain for over one year. MRI revealed an intradural mass with a cystic component, inferior to the spinal cord at L2‐L3, with no bony abnormality of the spine. At surgery, the mass was entirely intradural, inferior to the spinal cord and intimately attached to nerve roots of the cauda equina.
Leroy R. Sharer +3 more
openaire +1 more source
Clinicopathological characteristics of histiocytic sarcoma affecting the central nervous system in dogs. [PDF]
BackgroundHistiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation.
Crowe, Chelsea M +10 more
core
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Giant cell tumor of the thoracic spine: An unusual cause for spinal cord compression
Giant cell tumors (GCTs) of bone are uncommon neoplasms, typically located in the metaphysis of long bones, with rare occurrences in the spine, especially in the thoracic region.
Ghassen Gader +6 more
doaj +1 more source
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source

