Results 31 to 40 of about 1,190,854 (251)

Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial [PDF]

, 2008
Background: Patients with refractory angina have significant morbidity. This study aimed to compare two of the treatment options, Spinal Cord Stimulation (SCS) and Percutaneous Myocardial Laser Revascularisation (PMR) in terms of clinical outcomes and ...
Goldsmith KA, Buxton, M. J., I Hardy (45745), PM Schofield (45747), Sharples, L. D., Freeman, C, Sharples, LD, SN Khan (45742), Hardy I, M T Dyer (45740), MJ Buxton (45746), K A Goldsmith, Freeman, C., KA Goldsmith (45741), Schofield, PM, Khan, SN, I Hardy, Dyer M T, Hardy, I, Buxton MJ, Goldsmith, Kimberley; id_orcid, Schofield, P. M., Goldsmith, KA, LD Sharples (45743), M J Buxton, M T Dyer, Khan, S. N., S N Khan, P M Schofield, Khan SN, Freeman C, Dyer, MT, L D Sharples, Sharples LD, Schofield PM, Dyer, M. T., C Freeman (45744), C Freeman, Buxton, MJ, Schofield, MP, Hardy, I.   +40 more
core   +4 more sources

Activity-based recovery training with spinal cord epidural stimulation improves standing performance in cervical spinal cord injury

Journal of NeuroEngineering and Rehabilitation
Background Individuals with a clinically complete spinal cord injury are unable to stand independently without external assistance. Studies have shown the combination of spinal cord epidural stimulation (scES) targeted for standing with activity-based ...
Claudia A. Angeli, Enrico Rejc, Beatrice Ugiliweneza, Maxwell Boakye, Gail F. Forrest, Katelyn Brockman, Justin Vogt, Brittany Logsdon, Katie Fields, Susan J. Harkema   +9 more
doaj   +1 more source

Spinal cord stimulation: An emerging strategy for chronic pain relief after spinal cord injury

Neural Regeneration Research
Chronic pain following a spinal cord injury refers to pain that persists or recurs after the injury. This pain can manifest as burning, stinging, or sensations similar to electric shocks.
Qiwen Wang, Ying Zhang, Huifeng Zhang, Zhonghai Li   +3 more
doaj   +1 more source

Changes of intracellular sodium and potassium ion concentrations in frog spinal motoneurons induced by repetitive synaptic stimulation [PDF]

, 1982
A post-tetanic membrane hyperpolarization following repetitive neuronal activity is a commonly observed phenomenon in the isolated frog spinal cord as well as in neurons of other nervous tissues.
Ten Bruggencate, Gerrit, Grafe, Peter, Rimpel, Jürgen, Reddy, M. M., J. Rimpel, M.M. Reddy, P. Grafe, G. ten Bruggencate   +7 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robotic trunk perturbation magnitude affects standing postural responses in individuals with motor complete spinal cord injury receiving epidural stimulation

Scientific Reports
After a severe spinal cord injury (SCI), the human spinal circuitry receiving epidural stimulation can generate lower limb postural responses to sensory inputs associated with trunk perturbation.
Enrico Rejc, Collin D. Bowersock, Tanvi Pisolkar, Simone Zaccaron, Claudia A. Angeli, Gail F. Forrest, Sunil Agrawal, Susan J. Harkema   +7 more
doaj   +1 more source

Central nociceptive sensitization vs. spinal cord training: Opposing forms of plasticity that dictate function after complete spinal cord injury

Frontiers in Physiology, 2012
The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation.
Adam R Ferguson, J. Russell eHuie, Eric D Crown, James W Grau   +3 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source