Results 41 to 50 of about 1,115,479 (287)

Intracranial somatosensory responses with direct spinal cord stimulation in anesthetized sheep. [PDF]

PLoS ONE, 2013
The efficacy of spinal cord stimulators is dependent on the ability of the device to functionally activate targeted structures within the spinal cord, while avoiding activation of near-by non-targeted structures.
Oliver E Flouty, Hiroyuki Oya, Hiroto Kawasaki, Chandan G Reddy, Douglas C Fredericks, Katherine N Gibson-Corley, Nicholas D Jeffery, George T Gillies, Matthew A Howard   +8 more
doaj   +1 more source

Targeted transcutaneous spinal cord stimulation promotes persistent recovery of upper limb strength and tactile sensation in spinal cord injury: a pilot study

Frontiers in Neuroscience, 2023
Long-term recovery of limb function is a significant unmet need in people with paralysis. Neuromodulation of the spinal cord through epidural stimulation, when paired with intense activity-based training, has shown promising results toward restoring ...
Santosh Chandrasekaran, Nikunj A. Bhagat, Nikunj A. Bhagat, Richard Ramdeo, Sadegh Ebrahimi, Pawan D. Sharma, Doug G. Griffin, Adam Stein, Susan J. Harkema, Susan J. Harkema, Susan J. Harkema, Susan J. Harkema, Chad E. Bouton, Chad E. Bouton   +13 more
doaj   +1 more source

Repeatability of spinal reflexes of lower limb muscles evoked by transcutaneous spinal cord stimulation.

PLoS ONE, 2019
Transcutaneous electrical stimulation is a relatively new technique to evoke spinal reflexes in lower limb muscles. The advantage of this technique is that the spinal reflex responses can be obtained from multiple lower limb muscles simultaneously ...
Akira Saito, Yohei Masugi, Kento Nakagawa, Hiroki Obata, Kimitaka Nakazawa   +4 more
doaj   +1 more source

Effect of detraining on bone and muscle tissue in subjects with chronic spinal cord injury after a period of electrically-stimulated cycling: a small cohort study [PDF]

, 2009
Objective: To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after de-training or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury (SCI ...
Kakebeeke, T.H., Hunt, Kenneth J, KJ Hunt, P Eser, Coupaud, S., TH Kakebeeke, Perret, C., Hunt, K.J., Hunt, Kenneth, Coupaud, Sylvie, Frotzler, A., Frotzler, Angela, S Coupaud, Kakebeeke, Tanja H, Kakebeeke, Tanja, Perret, Claudio, Eser, Prisca, A Frotzler, Eser, P., C Perret   +19 more
core   +1 more source

Robotic Postural Training With Epidural Stimulation for the Recovery of Upright Postural Control in Individuals With Motor Complete Spinal Cord Injury: A Pilot Study

Neurotrauma Reports
Activity-based training and lumbosacral spinal cord epidural stimulation (scES) have the potential to restore standing and walking with self-balance assistance after motor complete spinal cord injury (SCI).
Enrico Rejc, Collin Bowersock, Tanvi Pisolkar, Isirame Omofuma, Tatiana Luna, Moiz Khan, Victor Santamaria, Beatrice Ugiliweneza, Claudia A Angeli, Gail F Forrest, Joel Stein, Sunil Agrawal, Susan J Harkema   +12 more
doaj   +1 more source

Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial [PDF]

, 2008
Background: Patients with refractory angina have significant morbidity. This study aimed to compare two of the treatment options, Spinal Cord Stimulation (SCS) and Percutaneous Myocardial Laser Revascularisation (PMR) in terms of clinical outcomes and ...
Goldsmith KA, Buxton, M. J., I Hardy (45745), PM Schofield (45747), Sharples, L. D., Freeman, C, Sharples, LD, SN Khan (45742), Hardy I, M T Dyer (45740), MJ Buxton (45746), K A Goldsmith, Freeman, C., KA Goldsmith (45741), Schofield, PM, Khan, SN, I Hardy, Dyer M T, Hardy, I, Buxton MJ, Goldsmith, Kimberley; id_orcid, Schofield, P. M., Goldsmith, KA, LD Sharples (45743), M J Buxton, M T Dyer, Khan, S. N., S N Khan, P M Schofield, Khan SN, Freeman C, Dyer, MT, L D Sharples, Sharples LD, Schofield PM, Dyer, M. T., C Freeman (45744), C Freeman, Buxton, MJ, Schofield, MP, Hardy, I.   +40 more
core   +4 more sources

Site-Specific Neuromodulation of Detrusor and External Urethral Sphincter by Epidural Spinal Cord Stimulation

Frontiers in Systems Neuroscience, 2020
Impairments of the lower urinary tract function including urine storage and voiding are widely spread among patients with spinal cord injuries. The management of such patients includes bladder catheterization, surgical and pharmacological approaches ...
Yuriy Sysoev, Yuriy Sysoev, Elena Bazhenova, Elena Bazhenova, Vsevolod Lyakhovetskii, Vsevolod Lyakhovetskii, Gleb Kovalev, Polina Shkorbatova, Regina Islamova, Natalia Pavlova, Natalia Pavlova, Oleg Gorskii, Oleg Gorskii, Oleg Gorskii, Natalia Merkulyeva, Natalia Merkulyeva, Natalia Merkulyeva, Dmitry Shkarupa, Pavel Musienko, Pavel Musienko, Pavel Musienko, Pavel Musienko   +21 more
doaj   +1 more source

Effect of detraining on bone strength in subjects with chronic spinal cord injury after a period of electrically-stimulated-cycling : a small cohort study [PDF]

, 2009
To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after detraining or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury.
Hunt, Kenneth, Coupaud, Sylvie, Frotzler, Angela, Kakebeeke, Tanja, Perret, Claudio, Eser, Prisca   +5 more
core   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source