Results 51 to 60 of about 1,190,854 (251)

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
Kühnerl, A., Sonnhof, U., Grafe, Peter
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Maladaptive spinal plasticity opposes spinal learning and recovery in spinal cord injury

Frontiers in Physiology, 2012
Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent manner even without input from the brain after complete SCI.
Adam R Ferguson, J Russell eHuie, Eric D Crown, Kyle M Baumbauer, Michelle A Hook, Sandra M Garraway, Kuan H Lee, Kevin C Hoy, James W Grau   +8 more
doaj   +1 more source

Evaluation of a re-engineered device for penile vibratory stimulation in men with spinal cord injury

, 2021
Study design: Cohort study Objectives: The purpose of this study was to evaluate the performance of a re-engineered device (Ferticare 2.0), which is replacing the previous standard (Ferticare 1.0) for penile vibratory stimulation in men with spinal cord ...
Stacy Elliott, Ivan Sunara, Dana A. Ohl, Seager, Stephen W J, Kajal Khodamoradi, Teodoro C. Aballa, Sunara, Ivan, Seager, Stephen W.J., Ohl, Dana A, Jensen, Christian F S, Elliott, Stacy, Jens Sonksen, Brackett, Nancy L., Nancy L. Brackett, Sonksen, Jens, Emad Ibrahim, Hultling, Claes, Stephen W. J. Seager, Khodamoradi, Kajal, Brackett, Nancy L, Christian F. S. Jensen, Aballa, Teodoro C., Ibrahim, Emad, Ohl, Dana A., Claes Hultling, Charles M. Lynne, Lynne, Charles M, Jensen, Christian F.S., Lynne, Charles M., Aballa, Teodoro C, Sonksen, J, Aballa, TC, Elliott, S, Ohl, DA, Jensen, CFS, Sunara, I, Lynne, CM, Hultling, C,, Ibrahim, E, Khodamoradi, K   +39 more
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Research hotspots and trends of spinal cord stimulation for neuropathic pain: a bibliometric analysis from 2004 to 2023

Perioperative Medicine
The purpose of this study is to systematically analyze the development trend, research hotspots, and future development direction on the treatment of neuropathic pain (NP) with spinal cord stimulation through bibliometric method.
Liwen Zhang, Zhenhua Li, Haiyan Gu, Jinyan Chen, Yanping Zhang, Yuanyuan Yu, Hexiang Wang   +6 more
doaj   +1 more source

Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons [PDF]

, 2008
Although most spinal cord injuries are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions.
Hunanyan, Arsen, John K. Robinson, Schnell, Lisa, Golshani, Roobeh, Li Lou, Roobeh Golshani, Lou, Li, Robinson, John, Lisa Schnell, Ghosh, Arko, Victor L. Arvanian, Schwab, Martin, Damien D. Pearse, Arvanian, Victor, Arsen Hunanyan, Martin E. Schwab, Arko Ghosh, Mendell, Lorne, James W. Fawcett, Lorne M. Mendell, Pearse, Damien, Fawcett, James   +21 more
core   +1 more source

Toward Perception‐Native Electronic Skin: Bio‐Inspired In‐/Near‐Sensor and Neuromorphic Computing for Humanoid Robots

Advanced Materials Technologies, EarlyView.
Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim, Chang‐Jae Beak, Jiyoung Park, Youngdo Jung, Sunjong Oh, Sin‐Hyung Lee, Bo‐Yeon Lee   +6 more
wiley   +1 more source

Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

Neural Regeneration Research
Promoting synaptic plasticity and inducing functional reorganization of residual nerve fibers hold clinical significance for restoring motor function following spinal cord injury.
Ya Zheng, Lingyun Cao, Dan Zhao, Qi Yang, Chunya Gu, Yeran Mao, Guangyue Zhu, Yulian Zhu, Jing Zhao, Dongsheng Xu   +9 more
doaj   +1 more source

Brain fMRI during orientation selective epidural spinal cord stimulation

Scientific Reports, 2021
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury.
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia   +13 more
doaj   +1 more source