Results 41 to 50 of about 114,217 (301)

Epidural combined optical and electrical stimulation induces high-specificity activation of target muscles in spinal cord injured rats

open access: yesFrontiers in Neuroscience, 2023
IntroductionEpidural electrical stimulation (EES) has been shown to improve motor dysfunction after spinal cord injury (SCI) by activating residual locomotor neural networks.
Xiao-Jun Guo   +8 more
doaj   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

open access: yesAdvanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

open access: yesAdvanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier   +3 more
wiley   +1 more source

Maladaptive spinal plasticity opposes spinal learning and recovery in spinal cord injury

open access: yesFrontiers in Physiology, 2012
Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent manner even without input from the brain after complete SCI.
Adam R Ferguson   +8 more
doaj   +1 more source

Brain fMRI during orientation selective epidural spinal cord stimulation

open access: yesScientific Reports, 2021
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury.
Antonietta Canna   +13 more
doaj   +1 more source

Evaluating optimized temporal patterns of spinal cord stimulation (SCS)

open access: yesBrain Stimulation, 2022
Background: Temporal patterns of stimulation represent a novel dimension for improving the efficacy of spinal cord stimulation to treat chronic neuropathic pain. Objective: We hypothesized that nonregular temporal patterns of stimulation designed using a
John E. Gilbert   +3 more
doaj   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon   +9 more
wiley   +1 more source

Research hotspots and trends of spinal cord stimulation for neuropathic pain: a bibliometric analysis from 2004 to 2023

open access: yesPerioperative Medicine
The purpose of this study is to systematically analyze the development trend, research hotspots, and future development direction on the treatment of neuropathic pain (NP) with spinal cord stimulation through bibliometric method.
Liwen Zhang   +6 more
doaj   +1 more source

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri   +6 more
wiley   +1 more source

Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

open access: yesNeural Regeneration Research
Promoting synaptic plasticity and inducing functional reorganization of residual nerve fibers hold clinical significance for restoring motor function following spinal cord injury.
Ya Zheng   +9 more
doaj   +1 more source

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