Results 41 to 50 of about 120,423 (202)

Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury. [PDF]

, 2019
AimThe activation of the TNFR2 receptor is beneficial in several pathologies of the central nervous system, and this study examines whether it can ameliorate the recovery process following spinal cord injury.MethodsEHD2-sc-mTNFR2 , an agonist specific ...
Bethea, John R, Blumenthal, Gary H, Bracchi-Ricard, Valerie, Fischer, Roman, Gerald, Marcus J, Kontermann, Roland E, Moxon, Karen A, Nandakumar, Bharadwaj, Pfizenmaier, Klaus, Ricard, Jerome, Williams, Raushaun   +10 more
core   +2 more sources

Polymer Fiber Probes Enable Optical Control of Spinal Cord and Muscle Function In Vivo [PDF]

, 2014
Restoration of motor and sensory functions in paralyzed patients requires the development of tools for simultaneous recording and stimulation of neural activity in the spinal cord.
Anikeeva, Polina Olegovna, Bizzi, Emilio, Caggiano, Vittorio, Canales, Andres, Froriep, Ulrich Paul, Koppes, Ryan, Lu, Chi, Ph. D. Massachusetts Institute of Technology, Selvidge, Jennifer G.   +7 more
core   +1 more source

Spinal cord stimulation for predominant low back pain in failed back surgery syndrome: study protocol for an international multicenter randomized controlled trial (PROMISE study) [PDF]

, 2013
Background: Although results of case series support the use of spinal cord stimulation in failed back surgery syndrome patients with predominant low back pain, no confirmatory randomized controlled trial has been undertaken in this patient group to date.
Annemans, Lieven, Desai, Mehul J, Greening, Christine, Kumar, Krishna, North, Richard B, Rigoard, Philippe, Shipley, Jane, Tan, Ye, Taylor, Rod S, Van den Abeele, Carine   +9 more
core   +5 more sources

Activity-based recovery training with spinal cord epidural stimulation improves standing performance in cervical spinal cord injury

Journal of NeuroEngineering and Rehabilitation
Background Individuals with a clinically complete spinal cord injury are unable to stand independently without external assistance. Studies have shown the combination of spinal cord epidural stimulation (scES) targeted for standing with activity-based ...
Claudia A. Angeli, Enrico Rejc, Beatrice Ugiliweneza, Maxwell Boakye, Gail F. Forrest, Katelyn Brockman, Justin Vogt, Brittany Logsdon, Katie Fields, Susan J. Harkema   +9 more
doaj   +1 more source

Spinal Cord Stimulation: An Update [PDF]

Neurotherapeutics, 2008
Spinal cord stimulation has been used in the treatment of many chronic pain disorders since 1967. In this update, the indications for spinal cord stimulation are reviewed with attention to recent publications. A focused review of the literature on abdominal and visceral pain syndromes is also provided.
Falowski, Steven, Celii, Amanda, Sharan, Ashwini   +2 more
openaire   +3 more sources

Electrode geometry and preferential stimulation of spinal nerve fibers having different orientations: a modeling study [PDF]

, 1992
In a computer modeling study of epidural spinal cord stimulation using a longitudinal array of electrode contacts, the effect of contact geometry and contact combination on the threshold voltages for stimulation of dorsal column (DC) fibers and dorsal ...
Holsheimer, Jan, Struijk, Johannes J.
core   +2 more sources

Central nociceptive sensitization vs. spinal cord training: Opposing forms of plasticity that dictate function after complete spinal cord injury

Frontiers in Physiology, 2012
The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation.
Adam R Ferguson, J. Russell eHuie, Eric D Crown, James W Grau   +3 more
doaj   +1 more source

Attrition with spinal cord stimulation [PDF]

British Journal of Neurosurgery, 2015
The aim of this prospective study was to investigate whether spinal cord stimulation (SCS) significantly reduces pain intensity for up to 18-month follow-up in patients with chronic neuropathic pain. Forty-eight patients were recruited. Patients rated their pain using a Visual analog scale (VAS) and pain-related disability using the Oswestry Disability
Mann, S.A., Sparkes, E., Duarte, R.V., Raphael, J.H.   +3 more
openaire   +4 more sources

Surgical Neurostimulation for Spinal Cord Injury. [PDF]

, 2017
Traumatic spinal cord injury (SCI) is a devastating neurological condition characterized by a constellation of symptoms including paralysis, paraesthesia, pain, cardiovascular, bladder, bowel and sexual dysfunction.
Cook, Gao, Halim, Heath, Hou, Karlsson, Krueger, Mohammadi, Partida, Pereira, Saitoh, Singh, Werndle   +12 more
core   +2 more sources

Changes in spinal cord hemodynamics reflect modulation of spinal network with different parameters of epidural stimulation

NeuroImage, 2020
In this study functional ultrasound (fUS) imaging has been implemented to explore the local hemodynamics response induced by electrical epidural stimulation and to study real-time in vivo functional changes of the spinal cord, taking advantage of the ...
Shanshan Tang, Carlos A. Cuellar, Pengfei Song, Riazul Islam, Chengwu Huang, Hai Wen, Bruce E. Knudsen, Ping Gong, U-Wai Lok, Shigao Chen, Igor A. Lavrov   +10 more
doaj