Results 71 to 80 of about 506,543 (349)

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri, Renata Maia, Pei Zhang, Liliana Agresti, Jelmer Sjollema, Mohammad‐Ali Shahbazi, Hélder A. Santos   +6 more
wiley   +1 more source

Epidural combined optical and electrical stimulation induces high-specificity activation of target muscles in spinal cord injured rats

Frontiers in Neuroscience, 2023
IntroductionEpidural electrical stimulation (EES) has been shown to improve motor dysfunction after spinal cord injury (SCI) by activating residual locomotor neural networks.
Xiao-Jun Guo, Ziyi Zhao, Jia-Qi Chang, Le-Wei He, Wen-Nan Su, Ting Feng, Can Zhao, Meng Xu, Jia-Sheng Rao   +8 more
doaj   +1 more source

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner, B. Katz, E. Gergens, E. H. Lambert, F. Colomo, F. H. Norris, H. Ter�v�inen, J. I. Simpson, K. Koizumi, K. Ricker, M. A. Kamenskaya, M. A. Kamenskaya, M. Otsuka, P. Grafe, R. C. Scaer, S. D. Erulkar, S. J. Oh, U. Sonnhof, U. Sonnhof, W. C. Wiederholt   +19 more
core   +1 more source

Mechanism of Action in Burst Spinal Cord Stimulation: Review and Recent Advances

Pain medicine (Malden, Mass.), 2019
Objective This is a comprehensive, structured review synthesizing and summarizing the current experimental data and knowledge about the mechanisms of action (MOA) underlying spinal cord stimulation with the burst waveform (as defined by De Ridder) in ...
K. Chakravarthy, Michael A. Fishman, X. Zuidema, C. Hunter, Robert Levy   +4 more
semanticscholar   +1 more source

Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications

Advanced Healthcare Materials, EarlyView.
The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho, Jeong Woo Chae, Young‐Jin Park, Ki Jun Yu, Sang Min Won   +4 more
wiley   +1 more source

Spinal cord stimulation trial can control pain caused by chronic limb-threatening ischemia

JPRAS Open
Background: Patients with chronic limb-threatening ischemia experience long-duration pain during ulcer treatment. Hence, painkillers are gradually increased, but adverse events often occur.
Yuta Terabe
doaj   +1 more source

Longitudinal Optogenetic Motor Mapping Revealed Structural and Functional Impairments and Enhanced Corticorubral Projection after Contusive Spinal Cord Injury in Mice [PDF]

, 2019
Current evaluation of impairment and repair after spinal cord injury (SCI) is largely dependent on behavioral assessment and histological analysis of injured tissue and pathways. Here, we evaluated whether transcranial optogenetic mapping of motor cortex
Chai, Zhi, Jin, Xiaoming, Qian, Jun, Wu, Wei, Xiong, Wenhui, Xu, Xiao-Ming   +5 more
core   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Brain fMRI during orientation selective epidural spinal cord stimulation

Scientific Reports, 2021
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury.
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia   +13 more
doaj   +1 more source

Evaluating optimized temporal patterns of spinal cord stimulation (SCS)

Brain Stimulation, 2022
Background: Temporal patterns of stimulation represent a novel dimension for improving the efficacy of spinal cord stimulation to treat chronic neuropathic pain. Objective: We hypothesized that nonregular temporal patterns of stimulation designed using a
John E. Gilbert, Tianhe Zhang, Rosana Esteller, Warren M. Grill   +3 more
doaj   +1 more source