Results 71 to 80 of about 517,553 (284)

Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]

, 1983
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor, Bennett, Cervero, Cervero, Cervero, Cervero, Coggeshall, Coggeshall, Dhanjal, Dhanjal, Dubuisson, Fry, Hentall, Hunt, Hökfelt, Kumazawa, Kumazawa, Light, Miletic, Murase, Price, Ruda, Sumal, W. Zieglgänsberger, Wall, Wall, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +29 more
core   +1 more source

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Nature Neuroscience, 2018
Epidural electrical stimulation (EES) of the spinal cord restores locomotion in animal models of spinal cord injury but is less effective in humans.
Emanuele Formento, K. Minassian, Fabien B. Wagner, Jean-Baptiste Mignardot, Camille G. Le Goff-Mignardot, Andreas Rowald, J. Bloch, S. Micera, M. Capogrosso, G. Courtine   +9 more
semanticscholar   +1 more source

Epidural combined optical and electrical stimulation induces high-specificity activation of target muscles in spinal cord injured rats

Frontiers in Neuroscience, 2023
IntroductionEpidural electrical stimulation (EES) has been shown to improve motor dysfunction after spinal cord injury (SCI) by activating residual locomotor neural networks.
Xiao-Jun Guo, Ziyi Zhao, Jia-Qi Chang, Le-Wei He, Wen-Nan Su, Ting Feng, Can Zhao, Meng Xu, Jia-Sheng Rao   +8 more
doaj   +1 more source

Perception threshold and electrode position for spinal cord stimulation [PDF]

, 1994
The perception threshold for epidural spinal cord stimulation in chronic pain management was analyzed on 3923 testing data obtained from 136 implanted patients.
Barolat, Giancarlo, He, Jiping, Holsheimer, Jan, Struijk, Johannes J.   +3 more
core   +3 more sources

Spinal cord stimulation trial can control pain caused by chronic limb-threatening ischemia

JPRAS Open
Background: Patients with chronic limb-threatening ischemia experience long-duration pain during ulcer treatment. Hence, painkillers are gradually increased, but adverse events often occur.
Yuta Terabe
doaj   +1 more source

Impaired transmission in the corticospinal tract and gait disability in spinal cord injured persons [PDF]

, 2010
Rehabilitation following spinal cord injury is likely to depend on recovery of corticospinal systems. Here we investigate whether transmission in the corticospinal tract may explain foot drop (inability to dorsiflex ankle) in persons with spinal cord ...
Barthélemy, Dorothy, Barthélemy, Dorothy, Biering-Sørensen, Fin, Biering-Sørensen, Fin, Conway, Bernard A, Conway, Bernard A., Holm-Nielsen, Jens Bo, Knudsen, Hanne, Knudsen, Hanne, Lundell, Hans Magnus Henrik, Lundell, Henrik, Nielsen, Jens Bo, Willerslev-Olsen, Maria, Willerslev-Olsen, Maria   +13 more
core   +1 more source

On the reflex mechanisms of cervical transcutaneous spinal cord stimulation in human subjects.

Journal of Neurophysiology, 2019
Transcutaneous and epidural electrical spinal cord stimulation techniques are becoming more valuable as electrophysiological and clinical tools. Recently, remarkable recovery of the upper limb sensorimotor function during cervical spinal stimulation was ...
Matija Milosevic, Yohei Masugi, Atsushi Sasaki, D. Sayenko, K. Nakazawa   +4 more
semanticscholar   +1 more source

Brain fMRI during orientation selective epidural spinal cord stimulation

Scientific Reports, 2021
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury.
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia   +13 more
doaj   +1 more source

Maladaptive spinal plasticity opposes spinal learning and recovery in spinal cord injury

Frontiers in Physiology, 2012
Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent manner even without input from the brain after complete SCI.
Adam R Ferguson, J Russell eHuie, Eric D Crown, Kyle M Baumbauer, Michelle A Hook, Sandra M Garraway, Kuan H Lee, Kevin C Hoy, James W Grau   +8 more
doaj   +1 more source

Evaluating optimized temporal patterns of spinal cord stimulation (SCS)

Brain Stimulation, 2022
Background: Temporal patterns of stimulation represent a novel dimension for improving the efficacy of spinal cord stimulation to treat chronic neuropathic pain. Objective: We hypothesized that nonregular temporal patterns of stimulation designed using a
John E. Gilbert, Tianhe Zhang, Rosana Esteller, Warren M. Grill   +3 more
doaj   +1 more source