Results 71 to 80 of about 768,571 (360)

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Minimally Invasive Spinal Surgery for Adult Spinal Deformity

Neurospine, 2018
The purpose of this review is to present the current techniques and outcomes of adult spine deformity (ASD) surgery using the minimally invasive spine surgery (MISS) approach.
Junseok Bae, Sang-Ho Lee
semanticscholar   +1 more source

Is There a Patient Profile That Characterizes a Patient With Adult Spinal Deformity as a Candidate for Minimally Invasive Surgery? [PDF]

, 2017
Study designRetrospective review.ObjectivesThe goal of this study was to evaluate the baseline characteristics of patients chosen to undergo traditional open versus minimally invasive surgery (MIS) for adult spinal deformity (ASD).MethodsA multicenter ...
Akbarnia, Behrooz A, Anand, Neel, Deviren, Vedat, Eastlack, Robert K, Fessler, Richard, International Spine Study Group, Kanter, Adam, Lafage, Virginie, Mummaneni, Praveen V, Mundis, Gregory M, Okonkwo, David, Park, Paul, Shaffrey, Christopher, Uribe, Juan, Wang, Michael   +14 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Proximal Junctional Kyphosis in Adult Spinal Deformity: Definition, Classification, Risk Factors, and Prevention Strategies [PDF]

, 2021
Hong Jin Kim, Jae Hyuk Yang, Dong‐Gune Chang, Se-Il Suk, Seung Woo Suh, Sang-Il Kim, Kwang‐Sup Song, Jong‐Beom Park, Woojin Cho   +8 more
openalex   +1 more source

Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery

Korean Journal of Spine, 2017
The purpose of this review is the current understanding of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity (ASD) surgery.
S. Hyun, Byoung Hun Lee, Jong-Hwa Park, Ki-Jeong Kim, T. Jahng, Hyun-Jib Kim   +5 more
semanticscholar   +1 more source

PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood

Mediators of Inflammation
Objectives. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease characterized by chronic spinal inflammation, arthritis, gut inflammation, and enthesitis.
Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai   +5 more
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance. [PDF]

, 2019
IntroductionMucopolysaccharidosis (MPS) IVA or Morquio A syndrome is an autosomal recessive lysosomal storage disorder (LSD) caused by deficiency of the N-acetylgalactosamine-6-sulfatase (GALNS) enzyme, which impairs lysosomal degradation of keratan ...
Akyol, Mehmet Umut, Alden, Tord D, Amartino, Hernan, Ashworth, Jane, Belani, Kumar, Berger, Kenneth I, Borgo, Andrea, Braunlin, Elizabeth, Eto, Yoshikatsu, Giugliani, Roberto, Gold, Jeffrey I, Harmatz, Paul, Hendriksz, Christian, Jester, Andrea, Jones, Simon A, Karsli, Cengiz, Mackenzie, William, Marinho, Diane Ruschel, McFadyen, Andrew, McGill, Jim, Mitchell, John J, MPS Consensus Programme Co-Chairs, MPS Consensus Programme Steering Committee, Muenzer, Joseph, Okuyama, Torayuki, Orchard, Paul J, Scarpa, Maurizio, Stevens, Bob, Thomas, Sophie, Walker, Robert, Wynn, Robert   +30 more
core   +2 more sources

Polyethylene microplastics transported to nucleus pulposus cells via macrophages-derived exosomes, and promote intervertebral disc degeneration through NAT10/SLC7A11 and ac4C modification

Ecotoxicology and Environmental Safety
Background: Intervertebral disc degeneration (IVDD) serves as the fundamental pathological basis for low back pain. Microplastics influence the organisms through exosomes-mediated communication.
Weilin Zhang, Kuize Liu, Zhencong Li, Dao Feng, Boyuan Zhou, Wei Zhao, Shengbang Huang, Zhiwen Dai, Jinguo Liang, Siyuan Chen, Yen Wei, Jinsong Wei   +11 more
doaj   +1 more source