Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis [PDF]
Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of microstructural model parameters has been used for assessment of tissue changes in neurodegenerative diseases and their ...
arxiv
A STUDY OF PYRUVIC ACID IN THE BLOOD AND SPINAL FLUID OF PATIENTS WITH LIVER DISEASE WITH AND WITHOUT HEPATIC COMA 1 [PDF]
Donald S. Amatuzio, Samuel Nesbitt
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Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló+5 more
wiley +1 more source
Monitoring morphometric drift in lifelong learning segmentation of the spinal cord [PDF]
Morphometric measures derived from spinal cord segmentations can serve as diagnostic and prognostic biomarkers in neurological diseases and injuries affecting the spinal cord. While robust, automatic segmentation methods to a wide variety of contrasts and pathologies have been developed over the past few years, whether their predictions are stable as ...
arxiv
Short Notes and Clinical Cases: Complete Degeneration of the Posterior Columns of the Spinal Cord with Chronic Polyneuritis in a Case of Widespread Carcinomatous Disease elsewhere [PDF]
F. Parkes Weber, T. R. Hill
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Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
DISEASES OF THE SPINAL CORD AND ITS MEMBRANES [PDF]
WILLIAM C. BRAISLIN
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PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou+7 more
wiley +1 more source
2008 Progress Report on Brain Research [PDF]
Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder+3 more
core
Some lesions of the spinal cord produced by experimental caisson disease [PDF]
A. E. Boycott, G. C. C. Damant
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