Results 201 to 210 of about 230,819 (312)
Chemical changes in the spinal cord in Friedreich's ataxia and motor neurone disease. [PDF]
, 1968 N. Robinson
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An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment
Advanced Science, EarlyView.Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su +12 more
wiley +1 more source
Cerebello-Thalamo-spinal Degeneration in Infancy: An Unusual Variant of Werdnig-Hoffmann Disease [PDF]
, 1965 R. M. Norman, J. M. Kày
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Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source
SOME CIRCULATORY RESPONSES TO VALSALVA'S MANOEUVRE IN PATIENTS WITH POLYNEURITIS AND SPINAL CORD DISEASE [PDF]
, 1962 W. E. Watson
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Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Advanced Science, EarlyView.Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie +10 more
wiley +1 more source
ART. XVI. An Inquiry concerning the Diseases and Functions of the Brain, the Spinal Cord, and the Nerves. [PDF]
A. Brigham
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Advanced Science, EarlyView.Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun +10 more
wiley +1 more source