Results 91 to 100 of about 1,858,166 (209)

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

The use of porous tantalum cages in the treatment of unremitting spondylodiscitis: a case report

Zdravniški Vestnik, 2018
Background: Unsuccessful medical treatment of pyogenic multifocal spondylodiscitis including signs of sepsis and unremitting pain is challenging. The aim of our report was to present a case of multilevel spondylodiscitis successfully treated by posterior
Samo Karel Fokter, Gregor Rečnik
doaj   +1 more source

Bioinspired Adaptive Surfaces for Intelligent Liquid Manipulation: Progressing From Passive and Active to Hybrid Strategies

Advanced Materials, EarlyView.
This review examines passive, active, and hybrid liquid manipulation strategies, highlighting hybrid approaches as an emerging route to reconcile energy efficiency with adaptive control. By actively reconstructing passive surfaces to store programmable interfacial energy, hybrid systems enable flexible yet low‐power liquid transport, with perspectives ...
Jiaqi Miao, Yiyuan Zhang, Liqiu Wang, Alan C. H. Tsang   +3 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

A Case Report of Moraxella catarrhalis Infection After Lumbar Spinal Fixation and Fusion [PDF]

Yehong Xie, Shunning Jiang, Qiaoling Liang, Xuezhu Hu, Dahai He, Xiaoheng Wu Chengdu University of Traditional Chinese Medicine Third Clinical Medical College/Affiliated Third Hospital, Pidu District Traditional Chinese Medicine Hospital, Chengdu ...
He D, Xie Y, Hu X, Jiang S, Liang Q, Wu X   +5 more
core  

Spinal hydatid disease

, 2002
Study design: Review article on spinal involvement of hydatid disease. Objectives: A better understanding of this rare but clinically challenging disease is intended.

core   +1 more source

Unravelling parasitic spinal infections: a narrative review on diagnosis, treatment strategies, and collaborative management approaches

GMS Hygiene and Infection Control
Introduction: Parasitic infections are more common in low hygiene regions but can occur in developed countries. They often cause significant morbidity and death, especially in the central nervous system. Some spinal infections are caused by Taenia solium,
Anand Kumar Das, Sona Bhardwaj, Rijhul Lahariya, Mainak Sinha, Saraj Kumar Singh, Simmi Kishore   +5 more
doaj   +1 more source

Risk Factors for Infectious Complications after Surgical Treatment of Spinal Metastases in Patients with Breast and Kidney Cancer

Travmatologiâ i Ortopediâ Rossii, 2019
Relevance. In patients with the most common malignant new growth such as breast, kidney and lung cancer the rate of spinal metastases amounts to 70%. Increasing number of surgical procedures results in growing frequency of postoperative complications ...
O. A. Smekalenkov, D. A. Ptashnikov, N. S. Zaborovskii, D. A. Mikhaylov, S. V. Masevnin, A. A. Denisov   +5 more
doaj   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source