Results 101 to 110 of about 1,858,166 (209)

Diagnostic value of percutaneous paramedian small-angle lateral intervertebral foramen Kambin’s triangle approach for lumbar puncture biopsy combined with tNGS-based multimodal etiological diagnosis in early spinal infection: a multicenter retrospective diagnostic yield study

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectiveTo validate the safety and multicenter technical feasibility of an innovatively designed percutaneous paramedian small-angle lateral intervertebral foramen Kambin’s triangle approach for lumbar puncture biopsy in early spinal infection (SI), and
Yuxin Gao   +14 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

open access: yesAdvanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti   +1 more
wiley   +1 more source

Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing [PDF]

open access: yes, 2003
One of the most devastating effects of damage to the upper spinal cord is the loss of the ability to breathe; patients suffering these injuries can be kept alive only with assisted ventilation. No known method for repairing these injuries exists.
Raisman, G., Li, Y., Decherchi, P.
core  

Clinical features of Q fever vertebral osteomyelitis: case reports and literature review

open access: yesFrontiers in Medicine
BackgroundThis study aims to characterize Q fever vertebral osteomyelitis based on our experience and literature review.MethodsBy reviewing all reported cases of Q fever vertebral osteomyelitis since the 21st century, we characterized the exposure ...
Tao Zhang   +3 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

The Utility of 3D Ultramicroscopy for Evaluating Cellular Therapies After Spinal Cord Injury

open access: yes, 2012
Cell therapies have shown promise for repairing the injured spinal cord in experimental models and are now being evaluated in clinical trials for the treatment of human spinal cord injury (SCI). To date, experimental evaluation of implanted cell survival,
Jährling, N   +4 more
core   +1 more source

Percutaneous CT-guided or endoscopic spinal biopsy with accurate pathogen detection for spinal infection

open access: yesFrontiers in Neurology
AimsIn this study, we aimed to analyze the pathogen detection results in spinal infections using percutaneous CT-guided biopsy or transforaminal endoscopic spinal biopsy.MethodsThis is a retrospective observational study of patients who underwent biopsy ...
Jinmei Chen   +7 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord injury [PDF]

open access: yes, 2013
This article provides the outcome of an investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord ...
Coupaud, Sylvie   +4 more
core   +1 more source

Preliminary research indicates that mechanical force through Pioze1 enhances local immunity during NPWT treatment for spinal infections

open access: yesFrontiers in Immunology
ObjectiveThis study aims to investigate the mechanism by which Negative Pressure Wound Therapy (NPWT) regulates local immune responses in spinal infection through Piezo1-mediated mechanical stress, and elucidate its potential role in the treatment of ...
Hao Xing   +4 more
doaj   +1 more source

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