Results 101 to 110 of about 236,106 (298)

A retrospective study of surgical treatment of spinal injuries with rehabilitation program [PDF]

, 2011
Introduction: Traumatic injuries of the spinal column are among the most devastating injuries in orthopedics. The primary goals of rehabilitation of these injuries are prevention of secondary complications, maximizing physical functioning and ...
Avdić, Dijana, Bojičić, Samir, Jaganjac, Amila, Katana, Bakir   +3 more
core   +2 more sources

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury [PDF]

, 2018
Many hundreds of thousands of people around the world are living with the long-term consequences of spinal cord injury and they need effective new therapies.
Albin, Barritt, Bartus, Biering-Sørensen, Bowes, Bradbury, Bradbury, Cafferty, Combrisson, Crespo, da Costa, Fawcett, Frank, Freedman, Gallucci, Garcia-Alias, Granger, Griffiths, Gutierrez-Quintana, Hamilton, Harris, Hilary Z Hu, Jefferson, Kwon, Kwon, Kwon, Lankhorst, Lee, Levine, Lin, Massey, Metz, Moore, Nashmi, Nick D Jeffery, Nicolas Granger, Nollet, Poncelet, Ravi V Bellamkonda, S Balakrishna Pai, Smith, Sylvestre, Tetzlaff, Toppercer, Watzlawick, Wicki, Yick   +46 more
core   +2 more sources

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Exploring positive adjustment in people with spinal cord injury. [PDF]

, 2013
This study explored adjustment in people with spinal cord injury; data from four focus groups are presented. Thematic analysis revealed four themes, managing goals and expectations, comparison with others, feeling useful and acceptance, showing ...
Burridge, J., Dibb, B., Donovan-Hall, M., Ellis-Hill, Caroline, Rushton, D.   +4 more
core   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Correlation of Body Mass Index and Disease Activity Score (DAS-28) in Patients with Rheumatoid Arthritis

National Journal of Community Medicine
Background: Rheumatoid Arthritis (RA) is the most common autoimmune disease. RA can cause permanent deformity and loss of productivity. The primary objective of the study was to evaluate the relationship of BMI with Disease Activity Score in RA patients.
Nishtha Agarwal, Shweta Dubey, Sanjeev Kapoor, Shriram Garg, AN Malaviya, Puja Nagpal   +5 more
doaj   +1 more source

The school lives of children and young people with a spinal cord injury [PDF]

, 2008
This research study was carried out by the Thomas Coram Research Unit, Institute of Education, University of London, between January and July 2008.The study was funded by The Back-Up Trust, an organisation working with spinally injured adults and ...
Knight, Abigail, Petrie, Pat, Potts, Patricia, Zuurmond, Maria   +3 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

A Rare Case of Cervical Intramedullary Spinal Cord Abscess

European Medical Journal Neurology
Intramedullary spinal cord abscess (ISCA) is an exceptionally rare pathological condition with the potential to affect any segment of the spinal cord.
Vanessa Chow, Ali Shanta, Jawaria Qureshi, Shyam Swarna   +3 more
doaj   +1 more source