Results 141 to 150 of about 120,291 (395)

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

Advanced Science, EarlyView.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian, Charlotte Maeve Dunne, Manfred Gossen, Matthias Hartlieb   +3 more
wiley   +1 more source

A Model for Spinal Muscular Atrophy Disease Registry for Iran [PDF]

Payesh
Objective(s): Spinal muscular atrophy is a rare genetic disease of neuromuscular and it is considered the main cause of death of newborns, which affects spinal motor neurons.
Hadiseh Azadi Cheshmekabodi, Farahnaz Sadoughi, Somayeh Nasiri   +2 more
doaj  

Mitochondrial dysfunction could precipitate motor neuron loss in spinal muscular atrophy [PDF]

, 2016
Hemi Malkki
openalex   +1 more source

Nusinersen in later-onset spinal muscular atrophy

Neurology, 2019
Objective To report results of intrathecal nusinersen in children with later-onset spinal muscular atrophy (SMA). Methods Analyses included children from a phase 1b/2a study (ISIS-396443-CS2; NCT01703988) who first received nusinersen during that study ...
B. Darras, C. Chiriboga, S. Iannaccone, K. Swoboda, J. Montes, L. Mignon, S. Xia, C. Bennett, K. Bishop, J. Shefner, Allison M. Green, P. Sun, I. Bhan, S. Gheuens, E. Schneider, W. Farwell, D. D. De Vivo   +16 more
semanticscholar   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

Advanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi, Mohammad Amin Yousefi, Liuchao Jin, Davood Rahmatabadi, Majid Baniassadi, Wei‐Hsin Liao, Mahdi Bodaghi, Mostafa Baghani   +7 more
wiley   +1 more source

Proximal spinal muscular atrophy 5q

Нервно-мышечные болезни, 2020
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article Editorial
doaj  

تجربیات زیسته یک مادر دارای کودک مبتلا به سندرم وردینگ هافمن: مطالعه موردی کیفی The Lived Experiences of the Mother of a Child with Werdnig-Hoffman Syndrome: A Qualitative Case Study [PDF]

, 2016
مقدمه: سندوم وردینگ هافمن جزء بیماری‌های تحلیل برنده و پیش‌رونده عصبی- نخاعی محسوب می‌شود که به صورت اتوزومی نهفته به ارث می ...
Araghian-Mojarad, F., Jouybari, L., Sanagoo, A.   +2 more
core  

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Patient Reported Impact of Symptoms in Spinal Muscular Atrophy (PRISM-SMA) [PDF]

, 2018
Phillip Mongiovi, Nuran Dilek, Connie Garland, Michael Hunter, John T. Kissel, Elizabeth Luebbe, Michael McDermott, Nicholas E. Johnson, Chad Heatwole   +8 more
openalex   +1 more source

Robotic Needle Steering for Percutaneous Interventions: Sensing, Modeling, and Control

Advanced Intelligent Systems, EarlyView.
This review examines recent advances in robotic needle steering for percutaneous interventions, highlighting closed‐loop sensing, physics‐informed tissue‐needle interaction modeling, and real‐time trajectory planning and control. It synthesizes innovations in deep learning, fiber‐optic feedback, and adaptive control strategies, and outlines emerging ...
Fangjiao Zhao, Ruixue Xu, Wujun Zhao, Xi‐Ming Sun, Yu Sun, Changsheng Dai   +5 more
wiley   +1 more source