Results 161 to 170 of about 80,027 (353)

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

Exploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du, Yujie Liu, Yuanchi Zhang, Yangyi Nie, Zili Xu, Ling Qin, Wei Zhang, Yuxiao Lai   +7 more
wiley   +1 more source

Hereditary distal muscular atrophy with vocal cord paralysis and sensorineural hearing loss: a dominant form of spinal muscular atrophy? [PDF]

, 1989
Eugen Boltshauser, W.J. Lang, Thomas Spillmann, E. Hof   +3 more
openalex   +1 more source

Microglial IKKβ Alters Central and Peripheral Immune Activity at Distinct Time Points After Spinal Cord Injury

Glia, EarlyView.
Microglial NF‐κB signaling increases M1‐like spinal microglia over time after spinal cord injury. Microglial NF‐κB signaling broadly affects gene expression in spinal cord. Microglial NF‐κB signaling modulates splenocytes acutely after spinal cord injury.
Micaela L. O'Reilly, Mariah J. Wulf, Theresa M. Connors, Ying Jin, Frank Bearoff, Julien Bouyer, Sandhya Kortagere, John R. Bethea, Veronica J. Tom   +8 more
wiley   +1 more source

Spinal muscular atrophy [PDF]

, 1995
Spinal Muscular Atrophy (SMA) is one of many neuromuscular diseases affect ing motor neurons and skeletal muscles. This disorder causes deterioration of the motor neurons (specifically the Anterior Horn Cells of the spinal cord). These motor neurons that
Nowak, Deborah
core   +1 more source

Cell adhesion molecule N-CAM is expressed by denervated myofibres in Werdnig-Hoffman and Kugelberg-Welander type spinal muscular atrophies. [PDF]

, 1987
F S Walsh, S.E. Moore, B D Lake
openalex   +1 more source

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

Glia, EarlyView.
In SOD1 mice, symptomatic spinal microglia and astrocytes show increased autophagy flux with greater dysfunction and SOD1 inclusions in astrocytes. Dysfunction was transient (end stage glia displayed control comparable levels of autophagy parameters). ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Nirma D. Perera, Subhavi De Silva, Doris Tomas, Brittany Cuic, Bradley J. Turner   +4 more
wiley   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, EarlyView., 2023
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

Mitochondrial functions in chronic spinal muscular atrophy. [PDF]

, 1980
J M Gobernado, Mario Gosálvez, Chandler S. Cortina, M Lousa, Catherine Riva, A. Gimeno   +5 more
openalex   +1 more source

Anxious Dads and Depressed Moms: Child Disability and the Mental Health of Parents

Health Economics, EarlyView.
ABSTRACT Having a child with a disability undoubtedly affects parents in many ways, including their well‐being. However, the specific mental health trajectories of parents, differentiated by the severity of impairments and parental roles, remain under‐explored. We investigate the mental‐health effects of having a child with a disability.
Derek Asuman, Tinna Laufey Ásgeirsdóttir, Johan Jarl   +2 more
wiley   +1 more source

Validation of the estimated Effect of Ankle Foot Orthoses on Spinal Cord Injury Gait Using Subject-Adjusted Musculoskeletal Models [PDF]

arXiv
Simulation of assistive devices on pathological gait through musculoskeletal models offers the potential and advantages of estimating the effect of the device in several biomechanical variables and the device characteristics ahead of manufacturing. In this study, we introduce a novel musculoskeletal modelling approach to simulate the biomechanical ...
arxiv