Results 231 to 240 of about 121,613 (384)

Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis   elegans model of spinal muscular atrophy [PDF]

, 2020
James R. Doyle, Céline Vrancx, Claudia Maios, Audrey Labarre, Shunmoogum A. Patten, J. Alex Parker   +5 more
openalex   +1 more source

A Network Centered on the Visual‐Motor Cortex Is Critically Involved in Postural Abnormality in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Postural abnormality (PA) is a key motor symptom in Parkinson's disease (PD) that leads to disability and death. However, the pathophysiology underlying PA is still unknown. Objective The objective of this study was to explore the neural patterns behind PAs and measures toward functional restoration using repetitive transcranial ...
Zhuang Wu, Sha Zhu, Ronghua Hong, Zhuoyu Zhang, Yanzi Peng, Jingxing Zhang, Lizhen Pan, Qiang Guan, Yuhui Chen, Lingjing Jin   +9 more
wiley   +1 more source

Application of Biomarkers in Spinal Muscular Atrophy. [PDF]

Int J Mol Sci
Gao C, Zhan Y, Chen H, Deng C.
europepmc   +1 more source

NANO GEL BASED CO-DELIVERY OF DICLOFENAC SODIUM AND LUTEOLIN: A PROMISING THERAPEUTIC STRATEGY FOR SPINAL MUSCULAR ATROPHY

Dr. Saravanan V. S., Karthiraja A. S., Sankaranarayanan A., Gowtham Prakash U., Gunavathy V., Guna V., Muniyan N., Metilda Stella Rani G.*
openalex   +1 more source

Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy

, 2011
Marco A. Passini, Jie Bu, Amy M. Richards, Cathrine Kinnecom, S. Pablo Sardi, Lisa M. Stanek, Yimin Hua, Frank Rigo, John Matson, Gene Hung, Edward M. Kaye, Lamya S. Shihabuddin, Adrian R. Krainer, C. Frank Bennett, Seng H. Cheng   +14 more
openalex   +2 more sources

Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review

Movement Disorders, EarlyView.
Abstract Background Most individuals with Parkinson's disease (PD) develop dysphagia during the course of their disease. It is crucial to comprehensively understand swallowing characteristics specific to PD for effective treatment. Objectives To systematically analyze and synthesize swallowing characteristics in people with PD compared with healthy ...
Kerstin Erfmann, Julia Hirschwald, Jule Hofacker, Katharina Winiker, Juliane Klann, Rainer Dziewas, Tobias Warnecke   +6 more
wiley   +1 more source

Pharmacokinetics of therapies approved for spinal muscular atrophy: A narrative review of current evidence. [PDF]

J Int Med Res
Sel EK, Gkrinia EMM, Roncato R, Vitezić D, Janković S, Belančić A, EACPT Early Career Clinical Pharmacologists Working Group.   +6 more
europepmc   +1 more source

Molecular characterization and copy number of SMN1, SMN2 and NAIP in Chinese patients with spinal muscular atrophy and unrelated healthy controls [PDF]

, 2015
Ping Fang, Liang Li, Jian Zeng, Wanjun Zhou, Weiqing Wu, Zeyan Zhong, Tizhen Yan, Jiansheng Xie, Jing Huang, Lin Li, Ying Zhao, Xiangmin Xu   +11 more
openalex   +1 more source

Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun, Damien Meng Kiat Leow, Loo Chien Wang, Michelle Yating Eio, Hiromi W. L. Koh, Zi Jian Khong, Gunaseelan Narayanan, Aloysius Kai Soon Teo, Richard Giadone, Radoslaw M. Sobota, Shi Yan Ng, Adrian Kee Keong Teo, Wei Yi Ong, Lee L. Rubin, Basil T. Darras, Crystal J. J. Yeo   +15 more
wiley   +1 more source

Newborn Screening for Spinal Muscular Atrophy in the UK: Use of Modelling to Identify Priorities for Ongoing Evaluation. [PDF]

Int J Neonatal Screen
Thokala P, Bessey A, Knowles R, Marshall J, Visintin C, Lawton M, Lombardo S.   +6 more
europepmc   +1 more source