Results 101 to 110 of about 888,799 (202)
Spinal Muscular Atrophy Diagnosed by Newborn Screening
, 2019 A panel of experts representing academic centers, family foundations and pharmaceutical industry came together to formulate a treatment algorithm for infants diagnosed via newborn screening (NBS) with Spinal muscular atrophy (SMA).
Vamshi K Rao +2 more
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The Spinal Muscular Atrophy Functional Classification System
Developmental Medicine &Child Neurology, EarlyView.The Spinal Muscular Atrophy Functional Classification System (SMAFCS) is a new four‐level functional mobility classification for spinal muscular atrophy, derived from Hammersmith Functional Motor Scale Expanded (HFMSE) thresholds and Functional Mobility Scale (FMS) groupings.
Jason J. Howard +5 more
wiley +1 more source
, 2015 Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder which affects α-motor neurons in anterior horns of spinal cord resulting in progressive muscle weakness.
Bohatá, Jana
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Journal of Periodontal Research, EarlyView.A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Considerations for Treatment in Clinical Care of Spinal Muscular Atrophy Patients
ChildrenSpinal Muscular Atrophy is a neurodegenerative disease which can lead to muscle weakness, paralysis, and in some cases death. There are many factors that contribute to the severity of symptoms and those factors can be used to determine the best course of
Stephanie Voight, Kapil Arya
doaj +1 more source
Therapeutic activity of modified U1 core spliceosomal particles
Nature Communications, 2016 Modification of the spliceosome is being tested as a potential therapy for exon-skipping diseases, such as spinal muscular atrophy (SMA). Here the authors show that 70K and stem loop IV structural elements of a modified U1 particle are essential for ...
Malgorzata Ewa Rogalska +6 more
doaj +1 more source
Surgical considerations based on oral and periodontal vascularization
Periodontology 2000, EarlyView.Abstract Objectives To synthesize current evidence on vascular and anastomotic patterns, emphasizing their operative implications for optimizing flap perfusion, neovascularization, and wound healing in periodontal and implant surgery, while accounting for anatomical variability and collateral circulation. Materials and Methods A comprehensive review of
Arvin Shahbazi +5 more
wiley +1 more source
Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes in spinal muscular atrophy (SMA) patients in Malaysia [RJ482.A83 W333 2008 f rb]. [PDF]
, 2007 Spinal Muscular Atrophy (SMA) adalah sejenis penyakit kelemahan saraf otot yang akhirnya menyebabkan kemerosotan otot. Penyakit ini disebabkan oleh mutasi pada gen Survival Motor Neuron 1 (SMN1).
Mohd Shamshudin, Wati @ Hayati
core +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Spinal muscular atrophy (Werdnig‑Hoffmann atrophy disease) [PDF]
, 2018 Introduction. Spinal muscular atrophy type 1 is an autosomal recessive neuromuscular disorder characterized by degeneration of the anterior horn cells in the spinal cord, leading to symmetric muscle weakness and atrophy.
Mariana A. RYZNYCHUK +4 more
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