Results 41 to 50 of about 82,042 (264)

Spontaneous Spinal Epidural Hematoma as a Potentially Important Stroke Mimic

Journal of Central Nervous System Disease, 2014
Hemiparesis develops in response to a wide range of neurological disorders, such as stroke, neoplasms and several inflammatory processes. Occasionally, it may also occur due to a lesion located in the high cervical spinal cord. In this concise review, we
Tetsu Akimoto, Takeshi Yamada, Soji Shinoda, Yasushi Asano, Daisuke Nagata   +4 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Unilateral fixation in the treatment of metastatic lesions of the spine [PDF]

Coluna/Columna
Objective: To evaluate the surgical outcome of patients with spinal metastases who underwent unilateral fixation using a pedicle fixation system. Methods: Seventeen patients with metastatic spinal lesions underwent surgical treatment for metastatic ...
Matheus Pippa Defino, Flavio Emanuel Gonçalves de Abreu, Thiago de Oliveira Dorigão, Helton L A Defino   +3 more
doaj   +1 more source

Comment on: “Challenging the Odds: Long‐Term Survival in Pediatric Diffuse Midline Glioma With H3 K27M and BRAF V600 Co‐Mutations Treated With Upfront Radiotherapy and Targeted Therapy”

Pediatric Blood &Cancer, EarlyView.
Natália Dassi, Andrea Maria Cappellano
wiley   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

An Unusual Presentation of Spinal Giant Cell Glioblastoma in a 21-Year-Old Female

Journal of Investigative Medicine High Impact Case Reports, 2019
Primary spinal cord giant cell glioblastoma multiforme of the thoracic spinal cord is a rarely-diagnosed primary spinal cord tumor in comparison to neoplasms in intracranial locations.
Benjamin J. Delgado BS, Leila Moosavi MD, Ericka Rangel BS, William Stull MD, Rahul Dev Polineni MD, Joseph Chen MD, Everardo Cobos MD   +6 more
doaj   +1 more source

Multiple meningiomas within the spinal canal: case report with 23 tumors Meningiomas intrarraqueanos múltiplos: relato de caso com 23 tumores

Arquivos de Neuro-Psiquiatria, 2005
In most series of neoplasms of the spinal canal, spinal cord and its leptomeninges, the incidence of meningioma group comprises approximately 25%. The incidence of multiple meningiomas is small when compared with the frequency of its single occurrence ...
José Alberto Gonçalves da Silva, Maurus Marques de Almeida Holanda, Antônio Fernandes de Araújo, Roberto Vieira de Mello   +3 more
doaj   +1 more source

4D‐Printable Poly(Thio)urethane Photoresins With Reactive Oxygen Species Responsiveness and Anti‐Inflammatory Functionality

Advanced Functional Materials, EarlyView.
This work introduces UV‐curable poly(thio)urethane (PSU) thermosets as 4D printable scaffolds responsive to oxidative stress. PSU networks with 100 wt.% polypropylene glycol (PPG) effectively suppress inflammatory markers in microglial cells to basal values.
Xabier Lopez de Pariza, Lolita Arévalo‐Lagos, Louise Breloy, Oihane Varela, Aitor Larrañaga, Juan F. Cadavid‐Vargas, Olaia Garagarza‐Goienetxea, Melissa Moya‐Granados, Vanessa Bagnarello, Haritz Sardon, Miryam Criado‐Gonzalez   +10 more
wiley   +1 more source

The Radiologists’ Guide to Spinal Separation Surgery: What Does the Surgeon Want to Know?

Diseases
Spinal tumours are an uncommon but significant cause of pain, fractures, instability, and cord compression, leading to poor quality of life and mortality.
Mohsin Khan, Labeeba Haq, Sai Niharika Gavvala, Petr Rehousek, Simon Hughes, Rajesh Botchu   +5 more
doaj   +1 more source