Results 161 to 170 of about 260,916 (317)

Electrical stimulation decreases neuralgic pain after trigeminal deafferentation

, 2008
Trigeminal nerve activity mediates head pain after cranial injuries, and also contributes to idiopathic syndromes such as cluster headache and trigeminal neuralgia. Nevertheless, chronic facial pain sometimes develops after lesion of the trigeminal nerve.
Treleaven-Hassard, S., Drummond, P.D.
core  

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Peripheral Sympathetic Sprouting Drives Neuropathic Pain via Spinal Microglial P2Y12 Activation in a Rat Spinal Nerve Ligation Model. [PDF]

J Pain Res
Yu T, Huang H, Li Z, Yan H.
europepmc   +1 more source

Fluoroscopy-Guided Lumbar Spinal Nerve Stimulation to Treat Chronic Scrotal Pain. [PDF]

Cureus, 2023
Haider N, Gargya A.
europepmc   +1 more source

KCNQ/M currents in sensory neurons: Significance for pain therapy

, 2003
Neuronal hyperexcitability is a feature of epilepsy and both inflammatory and neuropathic pain. M currents [I-K(M)] play a key role in regulating neuronal excitability, and mutations in neuronal KCNQ2/3 subunits, the molecular correlates of I-K(M), have ...
Main, M, Matthews, EA, Burbidge, SA, Brown, TA, Brown, DA, Passmore, GM, Marsh, SJ, Mistry, M, Selyanko, AA, Al-Qatari, M, Dickenson, AH   +10 more
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

CT-guided spinal nerve root adhesiolysis for refractory atypical symptoms in cervical disc herniation: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Xian Q, Mao-Jiang Y, Hong-Ying Y, Han-Feng Y, Xiao-Xue X, Yong D.   +5 more
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Spinal Mincle activation as a new model of neuroinflammation-associated neuropathic pain: comparison with spinal nerve ligation. [PDF]

Korean J Pain
Yang J, Kim WM, Jeong S, Bae HB, Choi JI.   +4 more
europepmc   +1 more source

Potential sex differences in activation of pain-related brain regions in nonhuman primates with a unilateral spinal nerve ligation. [PDF]

Neural Regen Res, 2023
Murata K, Nozawa K, Matsushita M, Yamashita A, Fujii R, Awaga Y, Hama A, Natsume T, Yoshida G, Matsuyama Y, Takamatsu H.   +10 more
europepmc   +1 more source