Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Sacrifice of chronically impaired spinal nerve roots in schwannomas with functional compensation by adjacent roots: A case report and literature review. [PDF]
Mandelli C +4 more
europepmc +1 more source
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Hope for 17 patients with chronic cluster headache: efficacy evaluation of upper cervical spinal nerve root release surgery (2020-2023). [PDF]
Mao-Jiang Y +8 more
europepmc +1 more source
Diffuse Leptomeningeal Glioneuronal Tumor Involving Circle of Willis and Spinal Nerve Roots. [PDF]
Lei X, Liu Y, Han F, Yu H, Deng C, He D.
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Multiple spinal nerve sheath tumors in a dog resembling schwannomatosis in humans. [PDF]
Tse JL +4 more
europepmc +1 more source
Involvement of the spinal γ-aminobutyric acid receptor in the analgesic effects of intrathecally injected hypertonic saline in spinal nerve-ligated rats. [PDF]
Karm MH +5 more
europepmc +1 more source
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang +6 more
wiley +1 more source
A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/Ca<sup>2+</sup>/CaMK2A/CREB pathway. [PDF]
Jiang M +14 more
europepmc +1 more source

