Results 201 to 210 of about 1,760,803 (361)

Spinal Dorsal Nerve [PDF]

, 2020
openaire   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/Ca²⁺/CaMK2A/CREB pathway. [PDF]

Mater Today Bio
Jiang M, Lu W, Zhuang J, Song J, Zhao Y, Zhou C, Zhou Y, Shu W, Zhu Z, Jiang L, Wu P, Wu A, Sheng S, Zhu S, Wang Z.   +14 more
europepmc   +1 more source

Anatomical study and clinical significance of the posterior ramus of the spinal nerve of the lumbar spine. [PDF]

Front Cell Dev Biol, 2022
Zhang Z, Liu J, Xu Y, Chen Z, Luo S, Zhang X, Wang G, Cheng L.   +7 more
europepmc   +1 more source

Analysis of the Posterior Ramus of the Lumbar Spinal Nerve: The Structure of the Posterior Ramus of the Spinal Nerve

Anesthesiology, 2013
Toshiyuki Saito, H. Steinke, T. Miyaki, Shiro Nawa, Kanae Umemoto, K. Miyakawa, Norimitsu Wakao, K. Asamoto, T. Nakano   +8 more
semanticscholar   +1 more source

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

Advanced Science, EarlyView.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang, Linlin Xu, Chenglong Pan, Ruonan Cao, Piao Zeng, Xinxing Lyu, Qingxia Hu, Zhenzhen Yan, Shuhong Huang, Ningning Dang   +9 more
wiley   +1 more source

Changes in Brain Activity and Functional Connectivity During Spinal Nerve Stimulation in a Rat Model of Overactive Bladder. [PDF]

Int Neurourol J
Sun H, Zhou Y, Liu Q, Li X, Liao L.
europepmc   +1 more source

Thoracic Spinal Nerve Neuromodulation Therapy for Diabetic Gastroparesis: A Proof-of-Concept Study. [PDF]

Clin Gastroenterol Hepatol, 2023
Karunaratne T, Yan Y, Eubanks A, Inman B, Rao S, Sharma A.   +5 more
europepmc   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Cholesterol metabolism and neuroinflammatory changes in a non-human primate spinal nerve ligation model. [PDF]

Sci Rep
Yamane H, Koyama S, Komatsu T, Tanaka T, Koguchi R, Watanabe H, Nishiura M, Yoshikawa S, Iimura T.   +8 more
europepmc   +1 more source