Results 31 to 40 of about 48,155 (306)

Correlative factors of post-dural puncture backache in cesarean section

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: Spinal anesthesia is an optional method chosen for cesarean section. One main reason for the decline of this method is backache. This study was conducted to investigate the factors associated with post-dural puncture backache in cesarean ...
Saeed Pasban Noghabi   +3 more
doaj  

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

The Effect of Spinal Needle Type on Post-Dural Puncture Headache in Spinal Anesthesia: Prospective Randomized Study

open access: yesEurasian Journal of Medicine
Background: Postdural puncture headache is a headache that occurs after a dura puncture, especially in caesarean sections, and afects patient comfort and mobilization.
Duygu Akyol   +3 more
doaj   +1 more source

Intracranial subdural hematoma after epidural anesthesia: a case report and review of the literature

open access: yesInternational Journal of Emergency Medicine, 2018
Background Intracranial subdural hematoma occurring as a result of a procedure that causes a puncture of the spinal dura mater is extremely rare, with less than 100 cases reported.
Victor Szeto   +2 more
doaj   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu   +10 more
wiley   +1 more source

Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Preclinical studies have demonstrated that a single injection of an adeno-associated virus (AAV) vector into the cerebrospinal fluid (CSF) can achieve widespread gene transfer throughout the central nervous system.
Christian Hinderer   +8 more
doaj   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

A rare complication of spinal anesthesia: Intracranial subdural hemorrhage

open access: yesArchives of Clinical and Experimental Surgery, 2015
Spinal (subarachnoid) anesthesia (SA) is a widely used general-purpose anesthesia. Postdural Puncture Headaches (PDPHs) represent one of the principal complications of spinal anesthesia.
Cengiz Kaplan   +6 more
doaj   +1 more source

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