Results 61 to 70 of about 49,169 (237)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

HEADACHES AFTER SPINAL ANESTHESIA AND THEIR LINK WITH RELATED FACTORS IN CANDIDATES FOR CESAREAN

open access: yesNurse and Holistic Care
Background: During a cesarean section, spinal anesthesia can result in post-dural puncture headaches. Objective: A group of female candidates for cesarean was studied to explore the link between post-spinal anesthesia headaches and factors, including ...
Kamel Abdi   +4 more
doaj   +1 more source

Mount Fuji Sign: A Rare Complication of Meningitis

open access: yesHaseki Tıp Bülteni, 2018
Acute bacterial meningitis is a critical condition also because of associated complications and sequelae besides being a life-threatening infection. The complications may develop due to disease itself, diagnostic procedures or treatment. Pneumocephaly is
Gönül Şengöz   +2 more
doaj   +1 more source

Spinal coning after lumbar puncture in a patient with undiagnosed giant cervical neurofibroma

open access: yesAnnals of Indian Academy of Neurology, 2013
Lumbar puncture in the presence of an intracranial tumor with raised intracranial pressure is known to have catastrophic consequences due to herniation of intracranial contents through the tentorial hiatus or foramen magnum. There are relatively few case
Prasad Krishnan, Siddhartha Roychowdhury
doaj   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

open access: yesBMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang   +10 more
wiley   +1 more source

Diet of bird‐like troodontid dinosaurs: synthesis of a contentious clade

open access: yesBiological Reviews, EarlyView.
ABSTRACT Troodontidae is a clade of small‐to medium‐sized maniraptoran theropods that mainly lived in Laurasia (modern Asia, North America and Europe) during the Jurassic and Cretaceous periods and are believed to have had a variety of diets. The uniqueness of troodontid teeth suggests that they diverged from the typical flesh‐based diet of non‐avian ...
Yui Chi Fan   +2 more
wiley   +1 more source

Combined spinal–epidural anesthesia for an elderly patient with proportionate dwarfism for laparotomy

open access: yesThe Indian Anaesthetists' Forum, 2016
Anesthesia in a dwarf patient may be challenging as various anatomical anomalies make both general and regional anesthesia difficult. These patients may have atlantoaxial instability, potential for airway obstruction, and associated respiratory problems ...
Teena Bansal   +2 more
doaj   +1 more source

Accuracy Evaluation Trial of Mixed Reality-Guided Spinal Puncture Technology. [PDF]

open access: yesTher Clin Risk Manag, 2023
Wu J   +9 more
europepmc   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

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