Results 41 to 50 of about 42,390 (204)

Infliximab-related tubercular spinal epidural abscess without osseous involvement in a patient with Crohn’s disease: A case report

Indian Spine Journal, 2021
Tubercular spinal epidural abscess without osseous involvement is an extremely rare presentation of spinal tuberculosis. We report a case of perianal Crohn’s disease, who developed a tubercular epidural abscess in lumbosacral spine without osseous ...
Phani Kiran Surapuraju, Srinivas M., Subramanian Swaminathan   +2 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Recurrent Spinal Tuberculosis with HIV Infection After Surgery: A Rare Case of Recurrence and Drug Resistance

, 2023
Kangpeng Li,* Bo Liu,* Qiang ZhangNational Center for Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiang Zhang ...
Liu B, Li K, Zhang Q
core  

METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis

Journal of Orthopaedic Surgery and Research
Background Spinal Tuberculosis (STB) constitutes a common form of tuberculosis and is more widespread in developing countries. Not only is it one of the principal causes of spinal deformity but also it may trigger severe neurological impairments, thereby
Lijun Feng, Mengqi Zhu, Xu Zhang, Ningkui Niu, Zhiyun Shi   +4 more
doaj   +1 more source

Early diagnosis of spinal tuberculosis by magnetic resonance: perfusion weighted imaging in a rabbit model

BMC Medical Imaging, 2022
Highlights 1. A rabbit spinal tuberculosis model was established. 2. Various parameters in the early MR-PWI analysis were different in two groups. 3. MR-PWI may provide valuable imaging evidence for diagnosis and treatment of spinal tuberculosis.
Xiaochen Liu, Yunlin Wang, Wenxiao Jia
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Costotransversectomy in thoracic spinal tuberculosis [PDF]

, 2016
CITATION: Botha, A. H. & Davis, J. H. 2016. Costotransversectomy in thoracic spinal tuberculosis. South African Orthopaedic Journal Orthopaedic Journal, 15(1):83-86, doi:10.17159/2309-8309/2016/v15n1a10.The original publication is available at http://www.
Davis, J. H., Botha, A. H.
core   +1 more source

Biportal Endoscopic Posterior Open‐Window Focal Debridement and Lavage for Sacroiliac Joint Tuberculosis

Arthroscopy Techniques, EarlyView.
Abstract Sacroiliac joint tuberculosis (SJT), although relatively uncommon, may lead to severe destruction and functional impairment of the sacroiliac joint. Surgical intervention is recommended for patients with significant joint destruction, mild cystic changes, or sacroiliac joint instability. Early bone fusion may be facilitated through drainage of
Wei Cheng, Wei Zhang, Hao Pan, Gaoyong Jia   +3 more
wiley   +1 more source

LncRNA HCG18 regulates the progression of spinal tuberculosis by modulating the hsa-miR-146a-5p/TGF-β1/SMADs pathway

Journal of Orthopaedic Surgery and Research
Spinal tuberculosis is the most common extrapulmonary tuberculosis, characterized by intervertebral disc destruction, which seriously affects people’s quality of life.
Feng Li, Hongdong Tan, Xiao Zhang, Xiaodong Zhao, Xiaopeng Li, Gaoyang Chen   +5 more
doaj   +1 more source