Results 51 to 60 of about 582,656 (221)

Analysis of the Value of Serum Biomarker LBP in the Diagnosis of Spinal Tuberculosis

Infection and Drug Resistance, 2022
Caili Lou,1,2 Jian Liu,2 Zhibo Ren,2 Jinke Ji,2 Hongbao Ma,2 Hui Dong,3 Linan Wang,2 Xu Zhang,3 Ningkui Niu1 1Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China; 2Clinical ...
Lou C, Liu J, Ren Z, Ji J, Ma H, Dong H, Wang L, Zhang X, Niu N   +8 more
doaj  

Lumbosacral spinal tuberculosis [PDF]

The Egyptian Orthopaedic Journal, 2015
Spinal tuberculosis accounts for more than 50% of musculoskeletal tuberculosis and mainly involves the dorsal and dorsolumbar regions. Involvement of the lumbosacral region in spinal tuberculosis is rare, with only few reported cases in the literature ...
Amit Agrawal, Vissa Shanthi, K. Mohan, G. Reddy   +3 more
doaj   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Missed opportunities for tuberculosis diagnosis. [PDF]

, 2011
BACKGROUND: In high tuberculosis (TB) burden, resource-poor countries, sputum smear microscopy remains the mainstay of diagnosis. The low sensitivity of this test means that patients with smear-negative but culture-positive TB pass undetected through the
Trejos, N, Bailey, SL, Roper, MH, Moore, DAJ, Huayta, M, López Alarcón, V   +5 more
core   +4 more sources

Evaluation of Investigations Suitable to Stop Treatment in Spinal Tuberculosis

Journal of Clinical Orthopaedics
Spinal tuberculosis is the most common extra pulmonary manifestation of tuberculosis and accounts for half of the cases of skeletal tuberculosis and 2 % of all tuberculosis cases.
Vishal Kumar, Parth Bansal, Sarvdeep Singh Dhatt, Tensubam Tomthin Meetei, Arvind Vatkar, Sachin Kale   +5 more
doaj   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

Atypical imaging of spinal tuberculosis: a case report and review of literature

The Pan African Medical Journal, 2016
This is a case report of spinal tuberculosis combined with sacroiliac joint tuberculosis, pulmonary tuberculosis, chest wall tuberculosis and tuberculous pleurisy and the image of the patient is rare, special and not typical and it looks like a halo sign.
Huijun Zhang, Zenghui Lu
doaj   +1 more source

Minimally invasive spinal surgery in spinal tuberculosis – A case report series

Interdisciplinary Neurosurgery, 2021
Spinal tuberculosis is increasing in prevalence in sub Saharan Africa as we find ourselves at the epicentre of immunosuppression secondary to a human immunodeficiency pandemic.
Adrian Kelly, Aftab Younus, Patrick Lekgwara   +2 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source