Results 71 to 80 of about 582,656 (221)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

Neurosurgical management of spinal tuberculosis and associated patient outcomes in Africa: a scoping review

open access: yesDiscover Medicine
Background Spinal tuberculosis, also known as Pott’s disease, is one of the commonest forms of skeletal tuberculosis. It accounts for about 50% of musculoskeletal tuberculosis. It leads to deformity of the spine and neurological conditions if not treated
Abdulbasit Opeyemi Muili   +16 more
doaj   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Mainland diversification and recent island lineages in the reduviid genus Tapirocoris: an integrative taxonomic framework with four new species

open access: yesInsect Science, EarlyView.
Using an integrative taxonomic framework that combines COI DNA barcodes, geometric morphometrics and phylogeography, we revise the assassin bug genus Tapirocoris and recover seven well‐supported species, including four newly described cryptic species.
Ping Zhao   +8 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Targeting peroxynitrite production in a model of persistent temporomandibular disorder comorbid with migraine

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman   +4 more
wiley   +1 more source

Human resources for control of tuberculosis and HIV-associated tuberculosis. [PDF]

open access: yes, 2005
The global targets for tuberculosis (TB) control were postponed from 2000 to 2005, but on current evidence a further postponement may be necessary.
Zachariah, R   +7 more
core  

Pejerrey (Odontesthes bonariensis) Under Siege: Main Infectious Diseases and Their Role in Aquaculture and Wild Populations Amidst Environmental Change

open access: yesJournal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez   +4 more
wiley   +1 more source

A tuberculosis directory, containing a list of institutions, associations and other agencies dealing with tuberculosis in the United States and Canada ...

open access: yes, 1911
Compiler: 1911- P.P. Jacobs.Directory for 1919 issued in 3 parts: 1. A directory of tuberculosis associations and committees in the United States. 2. A directory of dispensaries, clinics and classes for the special treatment of tuberculosis in the United
Jacobs, Philip Peter, 1879- comp.   +1 more
core  

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