Results 91 to 100 of about 534,301 (305)
In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]
, 1990 To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ +3 more
core
Kinetochore-independent chromosome segregation driven by lateral microtubule bundles
eLife, 2015 During cell division, chromosomes attach to spindle microtubules at sites called kinetochores, and force generated at the kinetochore-microtubule interface is the main driver of chromosome movement.
Christina C Muscat +4 more
doaj +1 more source
TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]
, 2015 The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi +3 more
core +1 more source
Self-Organization and Forces in the Mitotic Spindle.
Annual Review of Biophysics, 2016 At the onset of division, the cell forms a spindle, a precise self-constructed micromachine composed of microtubules and the associated proteins, which divides the chromosomes between the two nascent daughter cells.
N. Pavin, I. Tolic
semanticscholar +1 more source
Sensors, 2012 Bearing defects are one of the most important mechanical sources for vibration and noise generation in machine tool spindles. In this study, an integrated finite element (FE) model is proposed to predict the vibration responses of a spindle bearing ...
Hongrui Cao, Linkai Niu, Zhengjia He
doaj +1 more source
A possible influence of the spindle fibre on crossing-over in Drosophila [PDF]
, 1932 The distribution of genes in the second and third chromosomes of Drosophila melanogaster suggests that crossing-over may be influenced by the spindle fibre at least in neighboring regions.
Beadle, G. W.
core +2 more sources
Sensors, 2014 Thermoelectric energy harvesting is emerging as a promising alternative energy source to drive wireless sensors in mechanical systems. Typically, the waste heat from spindle units in machine tools creates potential for thermoelectric generation. However,
Sheng Li, Xinhua Yao, Jianzhong Fu
doaj +1 more source
Chatter Control by Spindle Speed Variation in High-Speed Milling [PDF]
, 2009 High-speed milling operations are often limited by regenerative vibrations. The aim of this paper is to analyze the effect of spindle speed variation on machine tool chatter in high-speed milling. The stability analysis of triangular and sinusoidal shape
Arnaud, Lionel +3 more
core +2 more sources
Mechanical stability of bipolar spindle assembly
, 2016 Assembly and stability of mitotic spindle is governed by the interplay of various intra-cellular forces, e.g. the forces generated by motor proteins by sliding overlapping anti-parallel microtubules (MTs) polymerized from the opposite centrosomes, the ...
Malgaretti, Paolo, Muhuri, Sudipto
core +1 more source
Journal of Neuroscience, 1995 The role of the endogenous circadian pacemaker in the timing of the sleep-wake cycle and the regulation of the internal structure of sleep, including REM sleep, EEG slow-wave (0.75–4.5 Hz) and sleep spindle activity (12.75–15.0 Hz) was investigated ...
D.-J. Dijk, C. Czeisler
semanticscholar +1 more source