Results 81 to 90 of about 437,835 (354)

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly. [PDF]

, 2018
Mitotic spindle disassembly after chromosome separation is as important as spindle assembly, yet the molecular mechanisms for spindle disassembly are unclear.
Avunie-Masala, Buvelot, Cheeseman, Chen, Cleary, Cormier, Cottingham, David G. Drubin, Foiani, Fridman, Georjana Barnes, Gruneberg, Hoyt, Hoyt, Hsu, Itziar Ibarlucea-Benitez, Jaqaman, Kang, Khmelinskii, Kotwaliwale, Longtine, Luke S. Ferro, Morawska, Movshovich, Murata-Hori, Nakajima, Nakajima, Nicholas, Nishimura, Norden, Petersen, Reck-Peterson, Saunders, Saunders, Shannon, Straight, Tarantino, Thomas, Varga, Woodruff, Woodruff, Xing, Zhang, Zimniak   +43 more
core   +1 more source

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

Advanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li, Yifan Pan, Chikahiro Imashiro, Chaolun Xu, Jianxian He, Jingao Xu, Kewei Song, Ze Zhang, Chen Gao, Junbo Jiang, Runhuai Yang, Kayo Hirose, Shinjiro Umezu   +12 more
wiley   +1 more source

Measurement of Spindle Rigidity by using a Magnet Loader

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
The static rigidity of a rotating spindle in the radial direction is investigated in this research. A magnetic loading device (magnet loader) has been developed for the measurement.
Taku YAMAZAKI, Atsushi MATSUBARA, Tomoya FUJITA, Toshiyuki MURAKI, Kohei ASANO, Kazuyuki KAWASHIMA   +5 more
doaj   +1 more source

Measuring and modeling polymer gradients argues that spindle microtubules regulate their own nucleation

, 2017
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Foster, Peter J., Fürthauer, Sebastian, Kaye, Bryan, Needleman, Daniel J., Shelley, Michael J., Stiehl, Olivia   +5 more
core   +1 more source

A novel chromosome segregation mechanism during female meiosis. [PDF]

, 2016
In a wide range of eukaryotes, chromosome segregation occurs through anaphase A, in which chromosomes move toward stationary spindle poles, anaphase B, in which chromosomes move at the same velocity as outwardly moving spindle poles, or both. In contrast,
Cortes, Daniel B, Kim, Taekyung, McNally, Francis J, McNally, Karen Perry, Panzica, Michelle T   +4 more
core   +1 more source

Biobased Bionic Spider Silk via Electrostatic Complexation for Simultaneously Harvesting Atmospheric Water and Triboelectric Energy

Advanced Functional Materials, EarlyView.
Bio‐based bionic spider silk and spider web are first prepared using polyelectrolyte complexation technique for the simultaneous harvesting of water and triboelectric energy. The advantage of this process lies on entirely bio‐based materials, fully green water‐processable procedures, extremely high production rate (99.36%), excellent fog harvesting ...
Qin Chen, Araz Rajabi‐Abhari, Tongtong Fu, Haonan Zhang, Siqi Huan, Liang Chen, Jinchao Li, Cheng Hao, Yaping Zhang, Ning Yan   +9 more
wiley   +1 more source

Kinetochore-independent chromosome segregation driven by lateral microtubule bundles

eLife, 2015
During cell division, chromosomes attach to spindle microtubules at sites called kinetochores, and force generated at the kinetochore-microtubule interface is the main driver of chromosome movement.
Christina C Muscat, Keila M Torre-Santiago, Michael V Tran, James A Powers, Sarah M Wignall   +4 more
doaj   +1 more source

A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells. [PDF]

, 2014
Dynamic instability, polarity, and spatiotemporal organization are hallmarks of the microtubule cytoskeleton that allow formation of complex structures such as the eukaryotic spindle. No similar structure has been identified in prokaryotes.
Agard, David A, Chaikeeratisak, Vorrapon, Coker, Joanna KC, Erb, Marcella L, Kraemer, James A, Nonejuie, Poochit, Pogliano, Joe   +6 more
core   +2 more sources

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source