A heat dissipation enhancing method for the high-speed spindle based on heat conductive paths
Advances in Mechanical Engineering, 2023 High-speed spindle systems could generate sufficient heat when they are operating and would cause thermal deformation that influences spindle accuracy. Heat dissipation is a common and effective way to remove the generated heat.
Yang Li +5 more
doaj +1 more source
Human TPX2 is required for targeting Aurora-A kinase to the spindle [PDF]
, 2002 Aurora-A is a serine-threonine kinase implicated in the assembly and maintenance of the mitotic spindle. Here we show that human Aurora-A binds to TPX2, a prominent component of the spindle apparatus.
Roman Körner +18 more
core +1 more source
Latrunculin A delays anaphase onset in fission yeast by disrupting an ase1-independent pathway controlling mitotic spindle stability [PDF]
, 2008 It has been proposed previously that latrunculin A, an inhibitor of actin polymerization, delays the onset of anaphase by causing spindle misorientation in fission yeast.
Meadows, John C., Millar, Jonathan B. A.
core +1 more source
eLife, 2022 During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage ...
Manuel Lera-Ramirez +2 more
doaj +1 more source
The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]
, 2009 Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye +15 more
core +1 more source
Balancing spindles with tools for finishing and boring machines
Trudy Odesskogo Politehničeskogo Universiteta, 2023 Finishing and boring machines are used in serial and mass production for processing parts of various shapes and deformation properties, namely liners, connecting rods, pistons, flanges, couplings, as well as body parts such as crankcases, blocks ...
Олександр Андрійович Оргіян +2 more
doaj +5 more sources
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly [PDF]
, 2009 Mitotic spindle formation and chromosome segregation depend critically on kinetochore-microtubule (KT-MT) interactions. A new protein, termed Spindly in Drosophila and SPDL-1 in C.
Erich A. Nigg +15 more
core +1 more source
Assembly of Silicon Micro-parts with Steel Spindles Using Low-Temperature Soldering [PDF]
, 2014 A new assembly method for silicon micro-parts with non-planar steel parts is proposed: low-temperature soldering. Existing techniques for micro-mechanical assemblies are analyzed and compared to the proposed method, the method is explained and validated on an existing product using functional tests.
Laurenz Notter, Jacques Jacot
openaire +1 more source
Borealin : a novel chromosomal passenger required for stability of the bipolar mitotic spindle [PDF]
, 2004 The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the central spindle in mitosis. Here, we describe Borealin, a novel member of the complex.
Erich A. Nigg +26 more
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Initial Characterization of two novel spindle proteins, CHICA and HURP [PDF]
, 2008 During mitotic spindle assembly, the sister chromatids have to be captured by kinetochore (K) -fibers (bundles of kinetochore microtubules; KMTs) to ensure stable attachment of the chromosomes.
Nagel, Susanna
core +1 more source