Results 1 to 10 of about 402,652 (266)

The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo.

PLoS Genetics, 2009
Females homozygous for a mutation in cellular island (cei) produce embryos with defects in cytokinesis during early development. Analysis of the cytoskeletal events associated with furrow formation reveal that these defects include a general delay in ...
Taijiro Yabe, Xiaoyan Ge, Robin Lindeman, Sreelaja Nair, Greg Runke, Mary C Mullins, Francisco Pelegri   +6 more
doaj   +1 more source

ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation

Frontiers in Cell and Developmental Biology, 2020
Ankyrin repeat and SOCS box (ASB) family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence of variable repeats. To date, the roles of ASB family members remain largely unknown.
Yuan Liu, Xiaoyan Li, Yongfu He, Hengjie Wang, Min Gao, Longsen Han, Danhong Qiu, Li Ling, Honglin Liu, Ling Gu   +9 more
doaj   +1 more source

The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]

Cell Division, 2013
Abstract Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Luehrig, Sandra, Kolb, Susanne, Mellies, Nadine, Nolte, Jessica   +3 more
openaire   +3 more sources

Comment on “Sperm Injection at the Para‐Polar Body Site in Piezo‐Intracytoplasmic Sperm Injection Improves Subsequent Early Development of Bovine Embryos”

Reproductive Medicine and Biology
Piezo‐intracytoplasmic sperm injection (piezo‐ICSI) is increasingly used to reduce mechanical damage during sperm injection. In the recent study by Ashibe et al., placing the first polar body (PB) at the 2 or 4 o'clock position (“para‐PB piezo”) improved
Bangbei Wan, Weiying Lu
doaj   +1 more source

Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells [PDF]

Iranian Journal of Medical Sciences
Background: In approximately 80% of colorectal cancer cases, mutations in the adenomatous polyposis coli (APC) gene disrupt the Wingless-related integration site (Wnt)/β-catenin signaling pathway, a crucial factor in carcinogenesis.
Firli Rahmah Primula Dewi, Sri Puji Astuti Wahyuningsih, Vuanghao Lim, Lionel Lian Aun In, Alfiah Hayati   +4 more
doaj   +1 more source

AGS3 and Gα_i3 Are Concomitantly Upregulated as Part of the Spindle Orientation Complex during Differentiation of Human Neural Progenitor Cells

Molecules, 2020
Adult neurogenesis is modulated by many Gi-coupled receptors but the precise mechanism remains elusive. A key step for maintaining the population of neural stem cells in the adult is asymmetric cell division (ACD), a process which entails the formation ...
Jackson L. K. Yip, Maggie M. K. Lee, Crystal C. Y. Leung, Man K. Tse, Annie S. T. Cheung, Yung H. Wong   +5 more
doaj   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science
The cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
doaj   +1 more source

Emerging role and function of SPDL1 in human health and diseases

Open Medicine
SPDL1 (spindle apparatus coiled-coil protein 1), also referred to as CCDC99, is a recently identified gene involved in cell cycle regulation. SPDL1 encodes a protein, hSpindly, which plays a critical role in the maintenance of spindle checkpoint ...
Feng Yuejiao, Tang Donghao, Wang Jie
doaj   +1 more source

Eg5 UFMylation promotes spindle organization during mitosis

Cell Death and Disease
UFMylation is a highly conserved ubiquitin-like post-translational modification that catalyzes the covalent linkage of UFM1 to its target proteins. This modification plays a critical role in the maintenance of endoplasmic reticulum proteostasis, DNA ...
Guangxu Li, Yuanjiang Huang, Wenbo Han, Liyi Wei, Hongjing Huang, Yingbao Zhu, Qiao Xiao, Zujia Wang, Wen Huang, Ranhui Duan   +9 more
doaj   +1 more source

Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1). [PDF]

Cancer Cell Int, 2022
Song P, Wusiman D, Li F, Wu X, Guo L, Li W, Gao S, He J.   +7 more
europepmc   +1 more source