Results 41 to 50 of about 25,078 (240)
iScience, 2021 Summary: Here we identify human Kinesin-5, Kif11/HsEg5, as a cellular target of Zika protease. We show that Zika NS2B-NS3 protease targets several sites within the motor domain of HsEg5 irrespective of motor binding to microtubules.
Liqiong Liu +3 more
doaj +1 more source
Biology Open, 2013 Summary In animal cells the centrosome is commonly viewed as the main cellular structure driving microtubule (MT) assembly into the mitotic spindle apparatus.
Nicolas Lecland +10 more
doaj +1 more source
Genetic Instability Due to Spindle Anomalies Visualized in Mutants of Dictyostelium
Cells, 2021 Aberrant centrosome activities in mutants of Dictyostelium discoideum result in anomalies of mitotic spindles that affect the reliability of chromosome segregation.
Mary Ecke +2 more
doaj +1 more source
Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes. [PDF]
PLoS ONE, 2011 Mammalian oocyte meiotic maturation involves oocyte polarization and a unique asymmetric division, but until now, the underlying mechanisms have been poorly understood.
Shao-Chen Sun +5 more
doaj +1 more source
Effect of Oxygen Content on Surface and Subsurface Integrity During Turning of Ti–6Al–4V
Advanced Engineering Materials, EarlyView.This study examines how oxygen content in the ambient atmosphere affects the surface and subsurface properties of Ti–6Al–4V during turning. Results show that oxygen does not influence surface roughness. However, machining in an extremely high vacuum‐adequate atmosphere increases surface hardness by up to 7.8% and induces compressive residual stresses ...
Benjamin Bergmann +3 more
wiley +1 more source
Influence of an Oxygen‐Free Atmosphere on Diamond‐Single‐Grain Scratching of Ti–6Al–4V
Advanced Engineering Materials, EarlyView.Single‐grain scratching of Ti–6Al–4V is investigated under controlled, oxygen‐free, and ambient atmospheres using a novel experimental setup with in situ high‐speed imaging. The approach enables direct observation of chip formation and adhesion under suppressed oxidation.
Berend Denkena +2 more
wiley +1 more source
The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]
Cell Division, 2013 Abstract Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Luehrig, Sandra +3 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease [PDF]
Biochemistry and Cell Biology, 2015 Emerging data implicates ubiquitination, a post-translational modification, in regulating essential cellular events, one of them being mitosis. In this review we discuss how various E3 ligases modulate the cortical proteins such as dynein, LGN, NuMa, Gα, along with polymerization, stability, and integrity of spindles.
Srivastava, Devika, Chakrabarti, Oishee
openaire +2 more sources
Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts
Advanced Functional Materials, EarlyView.Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett +15 more
wiley +1 more source