Results 61 to 70 of about 402,652 (266)

Manipulation of the oocyte: possible damage to the spindle apparatus

open access: yesReproductive BioMedicine Online, 2002
Oocytes are structured, polarized cells. For high developmental potential, it is essential that the distribution of organelles and molecules, and the function of meiotic spindles remain intact during handling of oocytes in assisted reproduction. Spindles are dynamic cell organelles. Spindle formation depends on activity of motor proteins, energy supply
Ursula, Eichenlaub-Ritter   +2 more
openaire   +2 more sources

Two major autoantigen—Antibody systems of the mitotic spindle apparatus [PDF]

open access: yesArthritis & Rheumatism, 1996
AbstractObjective. To characterize human autoantigen‐antibody systems related to the mitotic poles and spindles.Methods. Thirty‐seven human sera with autoantibodies staining mitotic poles and spindles in indirect immunofluorescence (IIF) studies were further characterized by immunofluorescence on mitotic cells and by immunoblotting and ...
L E, Andrade   +3 more
openaire   +2 more sources

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly [PDF]

open access: yes, 2009
Mitotic spindle formation and chromosome segregation depend critically on kinetochore-microtubule (KT-MT) interactions. A new protein, termed Spindly in Drosophila and SPDL-1 in C.
Erich A. Nigg   +15 more
core   +1 more source

Establishment and mitotic characterization of new Drosophila acentriolar cell lines from DSas-4 mutant

open access: yesBiology Open, 2013
Summary In animal cells the centrosome is commonly viewed as the main cellular structure driving microtubule (MT) assembly into the mitotic spindle apparatus.
Nicolas Lecland   +10 more
doaj   +1 more source

Genetic Instability Due to Spindle Anomalies Visualized in Mutants of Dictyostelium

open access: yesCells, 2021
Aberrant centrosome activities in mutants of Dictyostelium discoideum result in anomalies of mitotic spindles that affect the reliability of chromosome segregation.
Mary Ecke   +2 more
doaj   +1 more source

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

open access: yes, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye   +15 more
core   +1 more source

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

open access: yesAdvanced Science
As a major component of the cytoskeleton, intermediate filaments are generally considered to play a supporting role in mitotic cells. They also take part in the regulation of cell motility, proliferation, differentiation, and apoptosis.
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
doaj   +1 more source

Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes. [PDF]

open access: yesPLoS ONE, 2011
Mammalian oocyte meiotic maturation involves oocyte polarization and a unique asymmetric division, but until now, the underlying mechanisms have been poorly understood.
Shao-Chen Sun   +5 more
doaj   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki   +7 more
wiley   +1 more source

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