Results 61 to 70 of about 26,039 (180)
Exotic mitotic mechanisms [PDF]
, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
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Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease [PDF]
Biochemistry and Cell Biology, 2015 Emerging data implicates ubiquitination, a post-translational modification, in regulating essential cellular events, one of them being mitosis. In this review we discuss how various E3 ligases modulate the cortical proteins such as dynein, LGN, NuMa, Gα, along with polymerization, stability, and integrity of spindles.
Srivastava, Devika, Chakrabarti, Oishee
openaire +2 more sources
The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents [PDF]
, 1988 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
core
eLife, 2023 WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions. Recessive mutations in WDR62 cause structural brain abnormalities and account for the second most common cause of autosomal recessive primary microcephaly (MCPH), indicating ...
Claudia Dell'Amico +9 more
doaj +1 more source
The spindle assembly checkpoint [PDF]
, 2012 During mitosis and meiosis, the spindle assembly checkpoint acts to maintain genome stability by delaying cell division until accurate chromosome segregation can be guaranteed.
Taylor, Stephen S. +2 more
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Human Nek7-interactor RGS2 is required for mitotic spindle organization [PDF]
, 2015 The mitotic spindle apparatus is composed of microtubule (MT) networks attached to kinetochores organized from 2 centrosomes (a.k.a. spindle poles). In addition to this central spindle apparatus, astral MTs assemble at the mitotic spindle pole and attach
Stephen Doxsey (690848) +6 more
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Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles. [PDF]
PLoS ONE, 2015 The centrosome-associated C1orf96/Centriole, Cilia and Spindle-Associated Protein (CSAP) targets polyglutamylated tubulin in mitotic microtubules (MTs).
Shinya Ohta +3 more
doaj +1 more source
WHAMM is essential for spindle formation and spindle actin polymerization in maturing mouse oocytes [PDF]
, 2021 WHAMM (WAS Protein Homolog Associated with Actin, Golgi Membranes, and Microtubules) is involved in Golgi membrane association, microtubule binding, and actin nucleation as a nucleation-promoting factor, which activates the actin-related protein 2/3 ...
Ji-Su Kim +8 more
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Frontiers in Plant ScienceThe significance of heat stress in agriculture is ever-increasing with the progress of global climate changes. Due to a negative effect on the yield of staple crops, including wheat, the impairment of plant reproductive development triggered by high ...
Attila Fábián +6 more
doaj +1 more source
A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA).
PLoS ONE, 2022 The Rho family Guanine nucleotide exchange factor (GEF) ARHGEF17 (also known as TEM4) is a large protein with only 3 annotated regions: an N-terminal actin-binding domain, a Rho-specific dbl homology (DH)- pleckstrin homology (PH) type GEF domain and a ...
Diogjena Katerina Prifti +2 more
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