A molecular analysis of the microtubule associated protein MAP65-1 [PDF]
, 2006 Microtubules (MTs) play important roles in various cellular processes including cell division, organelle movement and the determination of cellular morphology. The dynamics and organization of microtubules are regulated by microtubule associated proteins
Hsin Yu, Chang
core
Advanced ScienceThe cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li +6 more
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Regulation der humanen Aurora-A Kinase und Identifikation potentieller Interaktionspartner [PDF]
, 2004 The error-free segregation of duplicated chromosomes during cell division is essential for the maintenance of an intact genome. This process is brought about by a highly dynamic bipolar array of microtubules, the mitotic spindle.
Kufer, Thomas
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Emerging role and function of SPDL1 in human health and diseases
Open MedicineSPDL1 (spindle apparatus coiled-coil protein 1), also referred to as CCDC99, is a recently identified gene involved in cell cycle regulation. SPDL1 encodes a protein, hSpindly, which plays a critical role in the maintenance of spindle checkpoint ...
Feng Yuejiao, Tang Donghao, Wang Jie
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Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation [PDF]
, 2011 Regulated spindle orientation maintains epithelial tissue integrity and stem cell asymmetric cell division. In Drosophila melanogaster neural stem cells (neuroblasts), the scaffolding protein Canoe (Afadin/Af-6 in mammals) regulates spindle orientation ...
Kenneth E. Prehoda +3 more
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Eg5 UFMylation promotes spindle organization during mitosis
Cell Death and DiseaseUFMylation is a highly conserved ubiquitin-like post-translational modification that catalyzes the covalent linkage of UFM1 to its target proteins. This modification plays a critical role in the maintenance of endoplasmic reticulum proteostasis, DNA ...
Guangxu Li +9 more
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Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1). [PDF]
Cancer Cell Int, 2022 Song P +7 more
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Importin β is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells [PDF]
, 2004 Spatial control is a key issue in cell division. The Ran GTPase regulates several fundamental processes for cell life, largely acting through importin molecules.
Di Fiore, Barbara +6 more
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A nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosis [PDF]
, 2013 The nucleus undergoes a dramatic reorganization as the cell prepares to segregate its duplicated chromosomes during cell division. For many years s, the prevailing view was that in open mitosis the nucleus completely disassembled during early mitotic ...
Yao, Changfu
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Organization of spindle microtubules in Ochromonas danica [PDF]
, 1980 The entire framework of microtubules (MTs) in the mitotic apparatus of Ochromonas danica is reconstructed (except at the spindle poles) from transverse serial sections.
Pillus, L, Tippit, DH, Pickett-Heaps, J
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